Estimating the establishment of local transmission and the cryptic phase of the COVID-19 pandemic in the USA.


Journal

medRxiv : the preprint server for health sciences
Titre abrégé: medRxiv
Pays: United States
ID NLM: 101767986

Informations de publication

Date de publication:
28 Aug 2020
Historique:
pubmed: 18 7 2020
medline: 18 7 2020
entrez: 18 7 2020
Statut: epublish

Résumé

We use a global metapopulation transmission model to study the establishment of sustained and undetected community transmission of the COVID-19 pandemic in the United States. The model is calibrated on international case importations from mainland China and takes into account travel restrictions to and from international destinations. We estimate widespread community transmission of SARS-CoV-2 in February, 2020. Modeling results indicate international travel as the key driver of the introduction of SARS-CoV-2 in the West and East Coast metropolitan areas that could have been seeded as early as late-December, 2019. For most of the continental states the largest contribution of imported infections arrived through domestic travel flows.

Identifiants

pubmed: 32676609
doi: 10.1101/2020.07.06.20140285
pmc: PMC7359534
pii:
doi:

Types de publication

Preprint

Langues

eng

Commentaires et corrections

Type : UpdateIn

Déclaration de conflit d'intérêts

Competing Interests M.E.H. reports grants from National Institute of General Medical Sciences, during the conduct of the study; A.V. reports grants and personal fees from Metabiota inc., outside the submitted work; M.C. and A.P.P. report grants from Metabiota inc., outside the submitted work. No other relationships or activities that could appear to have influenced the submitted work.

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Auteurs

Jessica T Davis (JT)

laboratory for the Modeling of Biological and Socio-technical Systems, Northeastern University, Boston, MA USA.

Matteo Chinazzi (M)

laboratory for the Modeling of Biological and Socio-technical Systems, Northeastern University, Boston, MA USA.

Nicola Perra (N)

Networks and Urban Systems Centre, University of Greenwich, London, UK.
laboratory for the Modeling of Biological and Socio-technical Systems, Northeastern University, Boston, MA USA.

Kunpeng Mu (K)

laboratory for the Modeling of Biological and Socio-technical Systems, Northeastern University, Boston, MA USA.

Ana Pastore Y Piontti (APY)

laboratory for the Modeling of Biological and Socio-technical Systems, Northeastern University, Boston, MA USA.

Marco Ajelli (M)

Bruno Kessler Foundation, Trento Italy.
Department of Epidemiology and Biostatistics, Indiana University School of Public Health, Bloomington, IN, USA.

Natalie E Dean (NE)

Department of Biostatistics, College of Public Health and Health Professions, University of Florida, Gainesville, USA.

Corrado Gioannini (C)

ISI Foundation, Turin, Italy.

Maria Litvinova (M)

ISI Foundation, Turin, Italy.

Stefano Merler (S)

Bruno Kessler Foundation, Trento Italy.

Luca Rossi (L)

ISI Foundation, Turin, Italy.

Kaiyuan Sun (K)

Fogarty International Center, NIH, USA.

Xinyue Xiong (X)

laboratory for the Modeling of Biological and Socio-technical Systems, Northeastern University, Boston, MA USA.

M Elizabeth Halloran (ME)

Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Department of Biostatistics, University of Washington, Seattle, WA. USA.

Ira M Longini (IM)

Department of Biostatistics, College of Public Health and Health Professions, University of Florida, Gainesville, USA.

Cécile Viboud (C)

Fogarty International Center, NIH, USA.

Alessandro Vespignani (A)

laboratory for the Modeling of Biological and Socio-technical Systems, Northeastern University, Boston, MA USA.
ISI Foundation, Turin, Italy.

Classifications MeSH