Molecular imaging of cardiac CXCR4 expression in a mouse model of acute myocardial infarction using a novel
68Ga
CXCR4/CXCL12 chemokine axis
Myocardial infarction
PET
mice
tracer
Journal
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
ISSN: 1532-6551
Titre abrégé: J Nucl Cardiol
Pays: United States
ID NLM: 9423534
Informations de publication
Date de publication:
12 2021
12 2021
Historique:
received:
02
07
2019
accepted:
08
06
2020
pubmed:
18
7
2020
medline:
25
3
2022
entrez:
18
7
2020
Statut:
ppublish
Résumé
The chemokine receptor CXCR4 and its ligand CXCL12 have been shown to be a possible imaging and therapeutic target after myocardial infarction (MI). The murine-based and mouse-specific At days 1-6 after MI, mice were intravenously injected with Noninvasive molecular imaging of cardiac CXCR4 expression using a novel, murine-based, and specific
Sections du résumé
BACKGROUND
The chemokine receptor CXCR4 and its ligand CXCL12 have been shown to be a possible imaging and therapeutic target after myocardial infarction (MI). The murine-based and mouse-specific
METHODS AND RESULTS
At days 1-6 after MI, mice were intravenously injected with
CONCLUSION
Noninvasive molecular imaging of cardiac CXCR4 expression using a novel, murine-based, and specific
Identifiants
pubmed: 32676914
doi: 10.1007/s12350-020-02262-6
pii: 10.1007/s12350-020-02262-6
pmc: PMC8709820
doi:
Substances chimiques
CXCR4 protein, mouse
0
Chemokine CXCL12
0
Cxcl12 protein, mouse
0
Gallium Radioisotopes
0
Radioactive Tracers
0
Receptors, CXCR4
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2965-2975Informations de copyright
© 2020. The Author(s).
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