Protective effect of adenosine triphosphate against sunitinib-related skin damage in rats.

Adenosine Triphosphate / pharmacology Animals Antineoplastic Agents / toxicity Glutathione / metabolism Male Malondialdehyde / metabolism Oxidative Stress / drug effects Protective Agents / pharmacology Rats, Wistar Skin / drug effects Skin Diseases / chemically induced Sunitinib / toxicity
Sunitinib adenosine triphosphate cutaneous side effects oxidative stress protective effect

Journal

Human & experimental toxicology
ISSN: 1477-0903
Titre abrégé: Hum Exp Toxicol
Pays: England
ID NLM: 9004560

Informations de publication

Date de publication:
Dec 2020
Historique:
pubmed: 18 7 2020
medline: 23 4 2021
entrez: 18 7 2020
Statut: ppublish

Résumé

Cutaneous side effects associated with sunitinib use are a major problem in patients receiving cancer treatment. The aim of this study was to investigate the protective effect of adenosine triphosphate (ATP) against possible skin damage resulting from sunitinib use in rats. Thirty Albino Winstar rats were divided into the following three groups: healthy controls (HCs,

Identifiants

DOI: 10.1177/0960327120940365 PMID: 32677474
pubmed: 32677474
doi: 10.1177/0960327120940365
doi:

Substances chimiques

Antineoplastic Agents 0
Protective Agents 0
Malondialdehyde 4Y8F71G49Q
Adenosine Triphosphate 8L70Q75FXE
Glutathione GAN16C9B8O
Sunitinib V99T50803M

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1737-1746

Auteurs

N Yıldırım (N)

Department of Medical Oncology, 64177Firat University Faculty of Medicine, Elazığ, Turkey.
ORCID: 0000-0001-8198-2605

A Karatas (A)

Department of Internal Medicine, 64177Firat University Faculty of Medicine, Elazıg, Turkey.

M Cengiz (M)

Department of Internal Medicine, Faculty of Medicine, 472600Biruni University, Istanbul, Turkey.

E Onalan (E)

Department of Internal Medicine, 64177Firat University Faculty of Medicine, Elazıg, Turkey.

G N Yazıcı (GN)

Department of Histology and Embryology, Faculty of Medicine, Binali Yıldırım University, Erzincan, Turkey.

M Sunar (M)

Department of Anatomy, Faculty of Medicine, Binali Yıldırım University, Erzincan, Turkey.

R Mammadov (R)

Department of Pharmacology, Faculty of Medicine, Binali Yıldırım University, Erzincan, Turkey.

A Coban (A)

Department of Biochemistry, Faculty of Medicine, Binali Yıldırım University, Erzincan, Turkey.

H Suleyman (H)

Department of Pharmacology, Faculty of Medicine, Binali Yıldırım University, Erzincan, Turkey.

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Classifications MeSH

questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Nucléotides › Ribonucléotides › Nucléotides adényliques › Adénosine triphosphate › Protective effect of adenosine triphosphate...
questionsmedicales.fr › Eucaryotes › Animaux › Protective effect of adenosine triphosphate...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antinéoplasiques › Protective effect of adenosine triphosphate...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Oligopeptides › Glutathion › Protective effect of adenosine triphosphate...
questionsmedicales.fr › Composés chimiques organiques › Aldéhydes › Malonaldéhyde › Protective effect of adenosine triphosphate...
questionsmedicales.fr › Phénomènes physiologiques › Stress physiologique › Stress oxydatif › Protective effect of adenosine triphosphate...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Agents protecteurs › Protective effect of adenosine triphosphate...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Rat Wistar › Protective effect of adenosine triphosphate...
questionsmedicales.fr › Système tégumentaire › Peau › Protective effect of adenosine triphosphate...
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies de la peau › Protective effect of adenosine triphosphate...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Indoles › Sunitinib › Protective effect of adenosine triphosphate...