Contactless electrospray ionization mass spectrometry for direct detection of analytes in living organisms.
contactless electrospray ionization
in vivo analysis
in vivo sampling
living organism
mass spectrometry
Journal
Journal of mass spectrometry : JMS
ISSN: 1096-9888
Titre abrégé: J Mass Spectrom
Pays: England
ID NLM: 9504818
Informations de publication
Date de publication:
Apr 2021
Apr 2021
Historique:
revised:
26
04
2020
received:
24
02
2020
accepted:
11
05
2020
pubmed:
18
7
2020
medline:
26
10
2021
entrez:
18
7
2020
Statut:
ppublish
Résumé
In this study, we developed contactless electrospray ionization mass spectrometry (ESI-MS) for in vivo analysis of living organisms in different applications. The in vivo sampling and direct analysis processess of living organisms were integrated into an operation that only requires the organism close to MS inlet that was applied to a high voltage. Living plants and animals were directly induced to generate spray ionization. Direct detection and in vivo monitoring of metabolites and chemical residues in various living organisms were successfully demonstrated. Analysis of a single sample could be completed within 30 s. Overall, contactless ESI-MS provides an attractive in vivo method to straightforward investigation of living organisms.
Substances chimiques
Pesticides
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e4539Subventions
Organisme : National Natural Science Foundation of China
ID : 21804053
Organisme : National Natural Science Foundation of China
ID : 41827804
Organisme : Fundamental Research Funds for the Central Universities
ID : 21618341
Informations de copyright
© 2020 John Wiley & Sons, Ltd.
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