Metastatic Calcinosis of Gastric Mucosa.


Journal

Journal of investigative medicine high impact case reports
ISSN: 2324-7096
Titre abrégé: J Investig Med High Impact Case Rep
Pays: United States
ID NLM: 101624758

Informations de publication

Date de publication:
Historique:
entrez: 18 7 2020
pubmed: 18 7 2020
medline: 30 4 2021
Statut: ppublish

Résumé

Calcinosis cutis refers to the deposition of calcium salts in the cutaneous and subcutaneous tissue and is frequently associated with inflammation. Gastric calcinosis can be classified into metastatic, dystrophic, and idiopathic; metastatic calcinosis is the most common type. In metastatic calcification, calcium salts are deposited in normal soft tissues in the setting of altered metabolism of serum calcium and phosphorus and is a rare and serious complication of chronic renal failure. The important factors contributing to the development of metastatic calcinosis are hypercalcemia, hyperphosphatemia, and an elevated calcium-phosphate product. The most striking feature of this diagnosis is the calcification around the large joints. While it mostly involves dermis of small and medium-sized vessels, it can rarely affect the mucosal layers of the gastrointestinal (GI) tract. Calcinosis presents as a marker for the presence of calcifications in other organs, such as heart or lung, which can be life-threatening. Patients rarely present with clinical symptoms of GI upset, dyspepsia, or epigastric pain that are attributed to calcinosis. If patients present with GI symptoms, infectious causes remain to be higher on the differential. We present a case of incidental finding of gastric mucosal calcinosis during the workup and treatment of dysphagia.

Identifiants

pubmed: 32677845
doi: 10.1177/2324709620940482
pmc: PMC7370329
doi:

Substances chimiques

Phosphorus 27YLU75U4W
Calcium SY7Q814VUP

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2324709620940482

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Auteurs

Vatsalya Kosuru (V)

Augusta University Medical Center, Medical College of Georgia, Augusta, GA, USA.

Azeem Mohammed (A)

Augusta University Medical Center, Medical College of Georgia, Augusta, GA, USA.

Rajan Kapoor (R)

Augusta University Medical Center, Medical College of Georgia, Augusta, GA, USA.

Khushali Jhaveri (K)

Medstar Washington Hospital Center, Washington, DC, USA.

Vidya Medepalli (V)

Augusta University Medical Center, Medical College of Georgia, Augusta, GA, USA.

Laura Mulloy (L)

Augusta University Medical Center, Medical College of Georgia, Augusta, GA, USA.

Sandeep Anand Padala (SA)

Augusta University Medical Center, Medical College of Georgia, Augusta, GA, USA.

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Classifications MeSH