Serum Tau Proteins as Potential Biomarkers for the Assessment of Alzheimer's Disease Progression.


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
15 Jul 2020
Historique:
received: 22 06 2020
revised: 10 07 2020
accepted: 13 07 2020
entrez: 19 7 2020
pubmed: 19 7 2020
medline: 20 2 2021
Statut: epublish

Résumé

Total tau (t-tau) and phosphorylated tau (p-tau) protein elevations in cerebrospinal fluid (CFS) are well-established hallmarks of Alzheimer's disease (AD), while the associations of serum t-tau and p-tau levels with AD have been inconsistent across studies. To identify more accessible non-invasive AD biomarkers, we measured serum tau proteins and associations with cognitive function in age-matched controls (AMC,

Identifiants

pubmed: 32679907
pii: ijms21145007
doi: 10.3390/ijms21145007
pmc: PMC7404390
pii:
doi:

Substances chimiques

Biomarkers 0
tau Proteins 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : National Research Foundation of Korea
ID : NRF-2015M3A9E2028884
Organisme : National Research Foundation of Korea
ID : 2016M3C7A1914451

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Auteurs

Eunjoo Nam (E)

Department of Pharmacology, College of Medicine, Gachon University, Incheon 21936, Korea.
Neuroscience Research Institute, Gachon University, Incheon 21565, Korea.

Yeong-Bae Lee (YB)

Neuroscience Research Institute, Gachon University, Incheon 21565, Korea.
Department of Neurology, Gil Medical Center, Gachon University, Incheon 21565, Korea.

Cheil Moon (C)

Department of Brain Science, Graduate School, Daegu Gyeungbuk Institute of Science and Technology, Daegu 42988, Korea.

Keun-A Chang (KA)

Department of Pharmacology, College of Medicine, Gachon University, Incheon 21936, Korea.
Neuroscience Research Institute, Gachon University, Incheon 21565, Korea.
Department of Health Sciences and Technology, GAIHST, Gachon University, Incheon 21936, Korea.

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