Anagen Effluvium after Methotrexate: An Idiosyncratic Reaction.

Anagen effluvium low dose methotrexate

Journal

International journal of trichology
ISSN: 0974-7753
Titre abrégé: Int J Trichology
Pays: India
ID NLM: 101534370

Informations de publication

Date de publication:
Historique:
received: 03 04 2020
revised: 15 04 2020
accepted: 17 04 2020
entrez: 21 7 2020
pubmed: 21 7 2020
medline: 21 7 2020
Statut: ppublish

Résumé

Low-dose methotrexate (MTX) is the backbone of treatment for extensive psoriasis vulgaris not responding to topical therapy. Since its induction for the treatment of psoriasis in the 1970, its short- and long-term side effect profile has been extensively studied. Hair loss with MTX has been reported mostly with high-dose MTX used in chemotherapy. Here, we report a case of guttate psoriasis who presented with acute-onset anagen effluvium following the administration of only two doses of MTX 7.5 mg per week.

Identifiants

pubmed: 32684684
doi: 10.4103/ijt.ijt_49_20
pii: IJT-12-93
pmc: PMC7362964
doi:

Types de publication

Case Reports

Langues

eng

Pagination

93-96

Informations de copyright

Copyright: © 2020 International Journal of Trichology.

Déclaration de conflit d'intérêts

There are no conflicts of interest.

Références

Int J Rheum Dis. 2010 Oct;13(4):288-93
pubmed: 21199463
Pharmacogenomics J. 2001;1(1):65-70
pubmed: 11913730
Ann Rheum Dis. 2004 Oct;63(10):1227-31
pubmed: 15361376
Indian J Dermatol Venereol Leprol. 2013 Sep-Oct;79(5):604-12
pubmed: 23974578
Arthritis Rheum. 2001 Jul;44(7):1515-24
pubmed: 11465701
J Am Acad Dermatol. 1989 Feb;20(2 Pt 1):249-56
pubmed: 2915060
Blood. 2002 Nov 15;100(10):3832-4
pubmed: 12411325
Pharmacogenetics. 2004 Nov;14(11):733-9
pubmed: 15564880
Arthritis Rheum. 2006 Feb;54(2):607-12
pubmed: 16447238

Auteurs

Preema Sinha (P)

Department of Dermatology, Armed Forces Medical College, Pune, Maharashtra, India.

Siddharth Bhatt (S)

Department of Dermatology, Armed Forces Medical College, Pune, Maharashtra, India.

Subramaniyan Radhakrishnan (S)

Department of Dermatology, Armed Forces Medical College, Pune, Maharashtra, India.

Shekhar Neema (S)

Department of Dermatology, Armed Forces Medical College, Pune, Maharashtra, India.

Anwita Sinha (A)

Department of Dermatology, Armed Forces Medical College, Pune, Maharashtra, India.

Classifications MeSH