Prediction of the level of consciousness using pupillometer measurements in patients with impaired consciousness brought to the emergency and critical care center.

We investigated whether the level of consciousness can be predicted using pupillometer measurements in patients with severe disturbance of consciousness. Patients with a Glasgow Coma Scale (GCS) of 3-8, except for those after cardiac arrest, were included. Pupillary contraction rate and contraction velocity were each measured using a pupillometer. Thirty-five patients were analyzed. At the time of discharge or changing hospitals, 16 patients had a GCS score of 3-13 and 19 patients had a GCS score of 14-15. In the non-sedative group at about the time of arrival at our hospital, average pupillary contraction rates were 18.36% in the GCS 3-13 group and 19.67% in the GCS 14-15 group ( Pupillometer measurements could predict level of consciousness of patients with severe consciousness disorder.

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© 2020 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine.

Déclaration de conflit d'intérêts

Approval of the research protocol: The study protocol was approved by the ethics committee of Tokyo Medical University (study approval no. T2019‐0247). Informed consent: Informed consent was obtained from all individual participants included in the study. We obtained comprehensive consent in writing from all patients, and revealed the information of this study. Registry and registration no. of the study/trial: This study was registered in the UMIN Clinical Trial Registry (UMIN000040000). Animal studies: N/A. Conflict of interest: None.