Learning curve for EUS-guided biliary drainage: What have we learned?

CUSUM ERCP EUS-guided EUS-guided biliary drainage biliary drainage biliary stricture learning curve

Journal

Endoscopic ultrasound
ISSN: 2303-9027
Titre abrégé: Endosc Ultrasound
Pays: China
ID NLM: 101622292

Informations de publication

Date de publication:
Historique:
pubmed: 21 7 2020
medline: 21 7 2020
entrez: 21 7 2020
Statut: ppublish

Résumé

EUS-guided-biliary drainage (EUS-BD) is an efficacious and safe option for patients who fail ERCP. EUS-BD is a technically challenging procedure. The aim of this study was to define the learning curve for EUS-BD. Consecutive patients undergoing EUS-BD by a single operator were included for a prospective registry over 6 years. Demographics, procedural information, adverse events, and follow-up data were collected. Nonlinear regression and CUSUM analyses were conducted for the learning curve. Technical success was defined as successful stent placement. Clinical success was defined as resolution of jaundice and/or at least a 30% reduction in the pretreatment bilirubin level within a week after placement or normalization of bilirubin within 30 days. Seventy-two patients were included in the study (53% male, mean age 67 years). Technical success was achieved in 69 patients (96%). Clinical success was achieved in 59/69 patients (86%). Seven patients (10%) had adverse events including bleeding (n = 6) and liver abscess (n = 1). The median procedural time was 59 min (range 36-138 min). This was achieved at the 32 Endoscopists experienced in EUS-BD are expected to achieve a reduction in procedural time over successive cases, with efficiency reached at 59 min and a learning rate of 32 cases. Continued improvement is demonstrated with additional experience, with mastery suggested after approximately 100 cases.

Sections du résumé

BACKGROUND AND OBJECTIVE OBJECTIVE
EUS-guided-biliary drainage (EUS-BD) is an efficacious and safe option for patients who fail ERCP. EUS-BD is a technically challenging procedure. The aim of this study was to define the learning curve for EUS-BD.
METHODS METHODS
Consecutive patients undergoing EUS-BD by a single operator were included for a prospective registry over 6 years. Demographics, procedural information, adverse events, and follow-up data were collected. Nonlinear regression and CUSUM analyses were conducted for the learning curve. Technical success was defined as successful stent placement. Clinical success was defined as resolution of jaundice and/or at least a 30% reduction in the pretreatment bilirubin level within a week after placement or normalization of bilirubin within 30 days.
RESULTS RESULTS
Seventy-two patients were included in the study (53% male, mean age 67 years). Technical success was achieved in 69 patients (96%). Clinical success was achieved in 59/69 patients (86%). Seven patients (10%) had adverse events including bleeding (n = 6) and liver abscess (n = 1). The median procedural time was 59 min (range 36-138 min). This was achieved at the 32
CONCLUSION CONCLUSIONS
Endoscopists experienced in EUS-BD are expected to achieve a reduction in procedural time over successive cases, with efficiency reached at 59 min and a learning rate of 32 cases. Continued improvement is demonstrated with additional experience, with mastery suggested after approximately 100 cases.

Identifiants

pubmed: 32687074
pii: 290107
doi: 10.4103/eus.eus_42_20
pmc: PMC7811715
doi:

Types de publication

Journal Article

Langues

eng

Pagination

392-396

Déclaration de conflit d'intérêts

None

Références

Gastrointest Endosc. 2016 Dec;84(6):941-946
pubmed: 27237786
Gastrointest Endosc. 2012 Dec;76(6):1133-41
pubmed: 23021167
Clin Gastroenterol Hepatol. 2012 Aug;10(8):920-4
pubmed: 22387254
Dig Endosc. 2018 Jan;30(1):38-47
pubmed: 28656640
Dig Dis Sci. 2016 Mar;61(3):684-703
pubmed: 26518417
World J Gastroenterol. 2015 Jan 21;21(3):820-8
pubmed: 25624715
Clin J Gastroenterol. 2014 Apr;7(2):94-102
pubmed: 24765215
Endoscopy. 2015 Sep;47(9):794-801
pubmed: 25961443
World J Gastroenterol. 2016 Apr 21;22(15):3945-51
pubmed: 27099437
Gastrointest Endosc. 2016 Jun;83(6):1218-27
pubmed: 26542374
Gastrointest Endosc. 2016 Feb;83(2):401-3
pubmed: 26773636
Gastrointest Endosc. 2010 Dec;72(6):1175-84, 1184.e1-3
pubmed: 20970787
Gastroenterol Res Pract. 2012;2012:680753
pubmed: 22654900
Endoscopy. 2001 Oct;33(10):898-900
pubmed: 11571690
World J Gastroenterol. 2016 Jan 21;22(3):1297-303
pubmed: 26811666
J Hepatobiliary Pancreat Sci. 2010 Sep;17(5):611-6
pubmed: 19806298
Therap Adv Gastroenterol. 2017 Jan;10(1):42-53
pubmed: 28286558
Am J Gastroenterol. 2006 Apr;101(4):892-7
pubmed: 16635233
Medicine (Baltimore). 2017 Jan;96(3):e5154
pubmed: 28099327
Endosc Ultrasound. 2018 Jan-Feb;7(1):4-9
pubmed: 29451164

Auteurs

Amy Tyberg (A)

Division of Gastroenterology, Rutgers Robert Wood Johnson University Hospital, New Brunswick, NJ, USA.

Avantika Mishra (A)

Division of Gastroenterology, Rutgers Robert Wood Johnson University Hospital, New Brunswick, NJ, USA.

Maggie Cheung (M)

Division of Gastroenterology, Rutgers Robert Wood Johnson University Hospital, New Brunswick, NJ, USA.

Prashant Kedia (P)

Methodist Dallas Medical Center, Dallas, TX, USA.

Monica Gaidhane (M)

Division of Gastroenterology, Rutgers Robert Wood Johnson University Hospital, New Brunswick, NJ, USA.

Cassandra Craig (C)

Methodist Dallas Medical Center, Dallas, TX, USA.

Paul R Tarnasky (PR)

Methodist Dallas Medical Center, Dallas, TX, USA.

Jose Celso Ardengh (JC)

Hospital das Clinicas da FMRPUSP, Sao Paulo, Brazil.

Michel Kahaleh (M)

Division of Gastroenterology, Rutgers Robert Wood Johnson University Hospital, New Brunswick, NJ, USA.

Classifications MeSH