Efficient hepatic delivery and protein expression enabled by optimized mRNA and ionizable lipid nanoparticle.
Codon optimization
Erythropoietin
Lipid nanoparticle
mRNA delivery
mRNA therapy
Journal
Bioactive materials
ISSN: 2452-199X
Titre abrégé: Bioact Mater
Pays: China
ID NLM: 101685294
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
received:
27
05
2020
revised:
02
07
2020
accepted:
04
07
2020
entrez:
22
7
2020
pubmed:
22
7
2020
medline:
22
7
2020
Statut:
epublish
Résumé
mRNA is a novel class of therapeutic modality that holds great promise in vaccination, protein replacement therapy, cancer immunotherapy, immune cell engineering
Identifiants
pubmed: 32691013
doi: 10.1016/j.bioactmat.2020.07.003
pii: S2452-199X(20)30130-4
pmc: PMC7355334
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1053-1061Informations de copyright
© 2020 [The Author/The Authors].
Déclaration de conflit d'intérêts
Z. L. is the founder of Suzhou Ribo Life Science Co. Ltd. The other authors declare no competing financial interests.
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