Pharmacokinetics, Activity, and Residue Elimination of

Animals Chickens / blood Coccidiostats / blood Drug Residues / chemistry Nitriles / blood Stereoisomerism Triazines / blood
activity chickens diclazuril enantiomers liquid chromatography tandem mass spectrometry residues stereoselective pharmacokinetics

Journal

Journal of agricultural and food chemistry
ISSN: 1520-5118
Titre abrégé: J Agric Food Chem
Pays: United States
ID NLM: 0374755

Informations de publication

Date de publication:
19 Aug 2020
Historique:
pubmed: 22 7 2020
medline: 22 1 2021
entrez: 22 7 2020
Statut: ppublish

Résumé

Diclazuril (DIC) is widely used as a racemic mixture to prevent and treat coccidiosis in farm animals, while the pharmacokinetics, bioactivity, and toxicity of DIC enantiomers are not known at all. This study first established a simple, sensitive, and reliable liquid chromatography tandem mass spectrometry method for separation of

Identifiants

DOI: 10.1021/acs.jafc.0c03091 PMID: 32692165
pubmed: 32692165
doi: 10.1021/acs.jafc.0c03091
doi:

Substances chimiques

Coccidiostats 0
Nitriles 0
Triazines 0
diclazuril K110K1B1VE

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

8987-8995

Auteurs

Meiyu Zhang (M)

National Reference Laboratory of Veterinary Drug Residues, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.

Jingli Qiu (J)

Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou 510642, China.

Xiaogui Shu (X)

National Reference Laboratory of Veterinary Drug Residues, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.

Xiaoling Tang (X)

National Reference Laboratory of Veterinary Drug Residues, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.

Xuefang Sha (X)

Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou 510642, China.

Li Wu (L)

Guangdong Huanong Hi-Tech Bio-Pharmaceutical Co. Limited, Guangzhou 510642, China.

Jun Fan (J)

School of Chemistry, South China Normal University, Guangzhou 510006, China.
ORCID: 0000-0003-2986-8551

Dongping Zeng (D)

National Reference Laboratory of Veterinary Drug Residues, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
ORCID: 0000-0002-2006-5755

Rujian He (R)

School of Chemistry, South China Normal University, Guangzhou 510006, China.

Weiguang Zhang (W)

School of Chemistry, South China Normal University, Guangzhou 510006, China.
ORCID: 0000-0002-3697-2990

Zhenling Zeng (Z)

National Reference Laboratory of Veterinary Drug Residues, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou 510642, China.

Rong Liu (R)

National Reference Laboratory of Veterinary Drug Residues, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.

Limin He (L)

National Reference Laboratory of Veterinary Drug Residues, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou 510642, China.
ORCID: 0000-0001-8051-3639

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Pharmacokinetics, Activity, and Residue Elimination of
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Oiseaux › Poulets › Pharmacokinetics, Activity, and Residue Elimination of
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antiparasitaires › Antiprotozoaires › Coccidiostatiques › Pharmacokinetics, Activity, and Residue Elimination of
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pollution de l'environnement › Charge corporelle › Résidus de médicaments › Pharmacokinetics, Activity, and Residue Elimination of
questionsmedicales.fr › Composés chimiques organiques › Nitriles › Pharmacokinetics, Activity, and Residue Elimination of
questionsmedicales.fr › Phénomènes chimiques › Phénomènes de chimie organique › Isomérie › Stéréoisomérie › Pharmacokinetics, Activity, and Residue Elimination of
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Triazines › Pharmacokinetics, Activity, and Residue Elimination of