Building biosecurity for synthetic biology.


Journal

Molecular systems biology
ISSN: 1744-4292
Titre abrégé: Mol Syst Biol
Pays: England
ID NLM: 101235389

Informations de publication

Date de publication:
07 2020
Historique:
entrez: 22 7 2020
pubmed: 22 7 2020
medline: 15 7 2021
Statut: ppublish

Résumé

The fast-paced field of synthetic biology is fundamentally changing the global biosecurity framework. Current biosecurity regulations and strategies are based on previous governance paradigms for pathogen-oriented security, recombinant DNA research, and broader concerns related to genetically modified organisms (GMOs). Many scholarly discussions and biosecurity practitioners are therefore concerned that synthetic biology outpaces established biosafety and biosecurity measures to prevent deliberate and malicious or inadvertent and accidental misuse of synthetic biology's processes or products. This commentary proposes three strategies to improve biosecurity: Security must be treated as an investment in the future applicability of the technology; social scientists and policy makers should be engaged early in technology development and forecasting; and coordination among global stakeholders is necessary to ensure acceptable levels of risk.

Identifiants

pubmed: 32692486
doi: 10.15252/msb.20209723
pmc: PMC7373080
doi:

Substances chimiques

DNA, Recombinant 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e9723

Informations de copyright

© 2020 The Authors. Published under the terms of the CC BY 4.0 license.

Références

Sci Eng Ethics. 2015 Aug;21(4):1065-83
pubmed: 25248872
Hastings Cent Rep. 2018 Jan;48 Suppl 1:S50-S55
pubmed: 29453843
BMC Proc. 2018 Jul 19;12(Suppl 8):11
pubmed: 30079102

Auteurs

Benjamin D Trump (BD)

US Army Corps of Engineers, Engineer Research and Development Center, Vicksburg, MS, USA.

S E Galaitsi (SE)

US Army Corps of Engineers, Engineer Research and Development Center, Vicksburg, MS, USA.

Evan Appleton (E)

Harvard University, Cambridge, MA, USA.

Diederik A Bleijs (DA)

Biosecurity Office, Netherlands National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.

Marie-Valentine Florin (MV)

International Risk Governance Center, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Jimmy D Gollihar (JD)

US Army Research Laboratory (ARL), Adelphi, MD, USA.

R Alexander Hamilton (RA)

United Nations Interregional Crime and Justice Research Institute (UNICRI), Turin, Italy.

Todd Kuiken (T)

Genetic Engineering & Society Center at North Carolina State University, Raleigh, NC, USA.

Filippa Lentzos (F)

King's College London, London, UK.

Ruth Mampuys (R)

Netherlands Commission on Genetic Modification (COGEM), Bilthoven, The Netherlands.

Myriam Merad (M)

French National Centre for Scientific Research, Paris, France.

Tatyana Novossiolova (T)

Center for the Study of Democracy, Sofia, Bulgaria.

Kenneth Oye (K)

International Risk Governance Center, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Massachusetts Institute of Technology, Cambridge, MA, USA.

Edward Perkins (E)

US Army Corps of Engineers, Engineer Research and Development Center, Vicksburg, MS, USA.

Natàlia Garcia-Reyero (N)

US Army Corps of Engineers, Engineer Research and Development Center, Vicksburg, MS, USA.

Catherine Rhodes (C)

University of Cambridge, Cambridge, UK.

Igor Linkov (I)

US Army Corps of Engineers, Engineer Research and Development Center, Vicksburg, MS, USA.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH