Influence of Second Generation Oral Contraceptive Use on Adaptations to Resistance Training in Young Untrained Women.
Journal
Journal of strength and conditioning research
ISSN: 1533-4287
Titre abrégé: J Strength Cond Res
Pays: United States
ID NLM: 9415084
Informations de publication
Date de publication:
01 Jul 2022
01 Jul 2022
Historique:
pubmed:
23
7
2020
medline:
24
6
2022
entrez:
23
7
2020
Statut:
ppublish
Résumé
Dalgaard, LB, Jørgensen, EB, Oxfeldt, M, Dalgaard, EB, Johansen, FT, Karlsson, M, Ringgaard, S, and Hansen, M. Influence of second generation oral contraceptive use on adaptations to resistance training in young untrained women. J Strength Cond Res 36(7): 1801-1809, 2022-The study purpose was to determine effects of using second generation oral contraceptives (OC) on muscle adaptations to resistance training in young untrained women. Twenty users and 18 nonusers of OC completed a 10-week supervised progressive resistance training program. Before and after the intervention, muscle cross-sectional area (mCSA) of the quadriceps was measured using magnetic resonance imaging and muscle fiber CSA (fCSA) was determined by immunohistochemistry. In addition, body composition (DXA, fat mass/fat-free mass), maximal isometric muscle strength (dynamometry), 5 repetition maximum (5RM) leg press strength, counter movement jump (CMJ) height, and average power using a modified Wingate test were determined. Serum hormone analysis ensured OC compliance and 4-day food records documented dietary intake. After the training period, quadriceps mCSA (OC: 11.0 ± 6.0% vs. non-OC: 9.2 ± 5.0%, p = 0.001), type II fCSA (OC: 19.9 ± 7.9% vs. non-OC: 16.6 ± 7.2%, p = 0.05), muscle strength (knee extension, knee flexion and 5RM, p < 0.001), and functional power (CMJ, AP, p < 0.001) were significantly increased with no significant difference between the groups. However, a tendency toward a greater increase in fat-free mass (FFM) in the OC group was observed (OC: 3.7 ± 3.8% vs. non-OC: 2.7 ± 3.5%, p = 0.08). Collectively, use of second generation OCs in young untrained women did not significantly improve adaptations to 10 weeks of resistance training compared with nonusers. The trend toward greater gains in FFM in the OC group warrant future studies.
Identifiants
pubmed: 32694286
pii: 00124278-202207000-00006
doi: 10.1519/JSC.0000000000003735
doi:
Substances chimiques
Contraceptives, Oral
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1801-1809Informations de copyright
Copyright © 2020 National Strength and Conditioning Association.
Références
Bojsen-Moller J, Magnusson SP, Rasmussen LR, Kjaer M, Aagaard P. Muscle performance during maximal isometric and dynamic contractions is influenced by the stiffness of the tendinous structures. J Appl Physiol 99: 986–994, 2005.
Bokhof B, Gunther AL, Berg-Beckhoff G, Kroke A, Buyken AE. Validation of protein intake assessed from weighed dietary records against protein estimated from 24 h urine samples in children, adolescents and young adults participating in the Dortmund Nutritional and Longitudinally Designed (DONALD) Study. Public Health Nutr 13: 826–834, 2010.
Brzycki M. Strength testing: Predicting a one-rep max from reps-to-fatigue. J Health, 64: 88–90, 1993.
Cermak NM, Res PT, de Groot LC, Saris WH, van Loon LJ. Protein supplementation augments the adaptive response of skeletal muscle to resistance-type exercise training: A meta-analysis. Am J Clin Nutr 96: 1454–1464, 2012.
Chidi-Ogbolu N, Baar K. Effect of estrogen on musculoskeletal performance and injury risk. Front Physiol 9: 1834, 2018.
Dalgaard LB, Dalgas U, Andersen JL, et al. Influence of oral contraceptive use on adaptations to resistance training. Front Physiol 10: 824, 2019.
de Jonge XAKJ, Boot CRL, Thom JM, Ruell PA, Thompson MW. The influence of menstrual cycle phase on skeletal muscle contractile characteristics in humans. J Physiol 530: 161–166, 2001.
EFSA Panel on Dietetic Products N, Allergies. Scientific opinion on dietary reference values for protein. EFSA J 10: 2557, 2012.
Elliott-Sale KJ, Smith S, Bacon J, et al. Examining the role of oral contraceptive users as an experimental and/or control group in athletic performance studies. Contraception 88: 408–412, 2013.
Elliott-Sale KJ, Tenforde AS, Parziale AL, Holtzman B, Ackerman KE. Endocrine effects of relative energy deficiency in sport. Int J Sport Nutr Exerc Metab 28: 335–349, 2018.
Folland JP, Williams AG. The adaptations to strength training: Morphological and neurological contributions to increased strength. Sports Med 37: 145–168, 2007.
Friden C, Hirschberg AL, Saartok T. Muscle strength and endurance do not significantly vary across 3 phases of the menstrual cycle in moderately active premenopausal women. Clin J Sport Med 13: 238–241, 2003.
Goldberg GR, Black AE, Jebb SA, et al. Critical evaluation of energy intake data using fundamental principles of energy physiology: 1. Derivation of cut-off limits to identify under-recording. Eur J Clin Nutr 45: 569–581, 1991.
Hansen M, Couppe C, Hansen CS, et al. Impact of oral contraceptive use and menstrual phases on patellar tendon morphology, biochemical composition, and biomechanical properties in female athletes. J Appl Physiol 114: 998–1008, 2013.
Hansen M, Langberg H, Holm L, et al. Effect of administration of oral contraceptives on the synthesis and breakdown of myofibrillar proteins in young women. Scand J Med Sci Sports 21: 62–72, 2011.
Hansen M, Miller BF, Holm L, et al. Effect of administration of oral contraceptives in vivo on collagen synthesis in tendon and muscle connective tissue in young women. J Appl Physiol 106: 1435–1443, 2009.
Herzberg SD, Motu’apuaka ML, Lambert W, et al. The effect of menstrual cycle and contraceptives on ACL injuries and laxity: A systematic review and meta-analysis. Orthop J Sports Med 5: 2325967117718781, 2017.
Hicks-Little CA, Thatcher JR, Hauth JM, Goldfuss AJ, Cordova ML. Menstrual cycle stage and oral contraceptive effects on anterior tibial displacement in collegiate female athletes. J Sports Med Phys Fitness 47: 255–260, 2007.
Kagan HM, Li W. Lysyl oxidase: Properties, specificity, and biological roles inside and outside of the cell. J Cell Biochem 88: 660–672, 2003.
Konopka JA, Hsue LJ, Dragoo JL. Effect of oral contraceptives on soft tissue injury risk, soft tissue laxity, and muscle strength: A systematic review of the literature. Orthop J Sports Med 7: 2325967119831061, 2019.
Kristiansen MS, Uhrbrand A, Hansen M, et al. Concomitant changes in cross-sectional area and water content in skeletal muscle after resistance exercise. Scand J Med Sci Sports 24: e260–268, 2014.
Lee CA, Lee-Barthel A, Marquino L, et al. Estrogen inhibits lysyl oxidase and decreases mechanical function in engineered ligaments. J Appl Physiol (1985) 118: 1250–1257, 2015.
Lee CW, Newman MA, Riechman SE. Oral contraceptive use impairs muscle gains in young women. FASEB J 23, 2009 (Abstract).
Lee H, Petrofsky JS, Daher N, Berk L, Laymon M. Differences in anterior cruciate ligament elasticity and force for knee flexion in women: Oral contraceptive users versus non-oral contraceptive users. Eur J Appl Physiol 114: 285–294, 2014.
Legro RS, Pauli JG, Kunselman AR, et al. Effects of continuous versus cyclical oral contraception: A randomized controlled trial. J Clin Endocrinol Metab 93: 420–429, 2008.
Morton RW, Murphy KT, McKellar SR, et al. A systematic review, meta-analysis and meta-regression of the effect of protein supplementation on resistance training-induced gains in muscle mass and strength in healthy adults. Br J Sports Med 52: 376–384, 2018.
Nichols AW, Hetzler RK, Villanueva RJ, Stickley CD, Kimura IF. Effects of combination oral contraceptives on strength development in women athletes. J Strength Cond Res 22: 1625–1632, 2008.
Pokorny MJ, Smith TD, Calus SA, Dennison EA. Self-reported oral contraceptive use and peripheral joint laxity. J Orthop Sports Phys Ther 30: 683–692, 2000.
Procter-Gray E, Cobb KL, Crawford SL, et al. Effect of oral contraceptives on weight and body composition in young female runners. Med Sci Sports Exerc 40: 1205–1212, 2008.
Rabe T, Bohlmann MK, Rehberger-Schneider S, Prifti S. Induction of estrogen receptor-alpha and -beta activities by synthetic progestins. Gynecol Endocrinol 14: 118–126, 2000.
Roberts MD, Haun CT, Mobley CB, et al. Physiological differences between low versus high skeletal muscle hypertrophic responders to resistance exercise training: Current perspectives and future research directions. Front Physiol 9: 834, 2018.
Romance R, Vargas S, Espinar S, et al. Oral contraceptive use does not negatively affect body composition and strength adaptations in trained women. Int J Sports Med, 40: 842–849, 2019.
Ruzic L, Matkovic BR, Leko G. Antiandrogens in hormonal contraception limit muscle strength gain in strength training: Comparison study. Croat Med J 44: 65–68, 2003.
Sakamaki-Sunaga M, Min S, Kamemoto K, Okamoto T. Effects of menstrual phase-dependent resistance training frequency on muscular hypertrophy and strength. J Strength Cond Res 30: 1727–1734, 2016.
Sarwar R, Niclos BB, Rutherford OM. Changes in muscle strength, relaxation rate and fatiguability during the human menstrual cycle. J Physiol 493: 267–272, 1996.
Shultz SJ, Levine BJ, Nguyen AD, et al. A comparison of cyclic variations in anterior knee laxity, genu recurvatum, and general joint laxity across the menstrual cycle. J Orthop Res 28: 1411–1417, 2010.
Shultz SJ, Wideman L, Montgomery MM, Beasley KN, Nindl BC. Changes in serum collagen markers, IGF-I, and knee joint laxity across the menstrual cycle. J Orthop Res 30: 1405–1412, 2012.
Smith LR, Barton ER. Smash—Semi-automatic muscle analysis using segmentation of histology: A MATLAB application. Skelet Muscle 4: 21, 2014.
Suchomel TJ, Nimphius S, Stone MH. The importance of muscular strength in athletic performance. Sports Med 46: 1419–1449, 2016.
Sung E, Han A, Hinrichs T, et al. Effects of follicular versus luteal phase-based strength training in young women. Springerplus 3: 668, 2014.
Sung ES, Kim JH. The resistance training effects of different weight level during menstrual cycle in female. J Exerc Rehabil 15: 249–253, 2019.
Torstveit MK, Sundgot-Borgen J. Participation in leanness sports but not training volume is associated with menstrual dysfunction: A national survey of 1276 elite athletes and controls. Br J Sports Med 39: 141–147, 2005.
Verrilli LE, Landry M, Blanchard H. Contraceptive choices and menstrual patterns in high level female athletes. Fertil Steril 108: E122, 2017.
Volpi E, Lucidi P, Bolli GB, Santeusanio F, De Feo P. Gender differences in basal protein kinetics in young adults. J Clin Endocrinol Metab 83: 4363–4367, 1998.
Wikstrom-Frisen L, Boraxbekk CJ, Henriksson-Larsen K. Effects on power, strength and lean body mass of menstrual/oral contraceptive cycle based resistance training. J Sports Med Phys Fitness 57: 43–52, 2017.