Patient blood management in elective bypass cardiac surgery: A 2-step single-centre interventional trial to analyse the impact of an educational programme and erythropoiesis stimulation on red blood cell transfusion.
Anaemia
Cardiac surgery
Erythropoietin
Iron deficiency
Red blood cell transfusion
Journal
Contemporary clinical trials communications
ISSN: 2451-8654
Titre abrégé: Contemp Clin Trials Commun
Pays: Netherlands
ID NLM: 101671157
Informations de publication
Date de publication:
Sep 2020
Sep 2020
Historique:
received:
03
03
2020
revised:
20
06
2020
accepted:
12
07
2020
entrez:
23
7
2020
pubmed:
23
7
2020
medline:
23
7
2020
Statut:
epublish
Résumé
Anaemia and iron deficiency are frequent in patients scheduled for cardiac surgery. Perioperative patient blood management (PBM) is widely recommended in current practice guidelines. The aim of this protocol is to analyse the effect of a global perioperative PBM programme on the red blood cell (RBC) transfusion ratio, morbidities and rehabilitation score in elective cardiac surgery.This study is a prospective, single-centre trial with a 2-step protocol, A and B, as follows: A: non-drug intervention: the caregiver is given a blood management educational programme; B: drug intervention: systematic correction of perioperative iron, vitamin deficiencies, and anaemia. This study was designed to enrol 900 patients (500 in group A and 400 in group B) in a rolling period starting at anaesthesia consultation and ending 3 months after surgery. The primary ClinicalTrials.gov, NCT04040023: registered 29 July 2019.
Identifiants
pubmed: 32695923
doi: 10.1016/j.conctc.2020.100617
pii: S2451-8654(20)30101-0
pii: 100617
pmc: PMC7365967
doi:
Banques de données
ClinicalTrials.gov
['NCT04040023']
Types de publication
Journal Article
Langues
eng
Pagination
100617Informations de copyright
© 2020 Published by Elsevier Inc.
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