The 5-Year Incidence of Mental Disorders in a Population-Based ICU Survivor Cohort.
Journal
Critical care medicine
ISSN: 1530-0293
Titre abrégé: Crit Care Med
Pays: United States
ID NLM: 0355501
Informations de publication
Date de publication:
08 2020
08 2020
Historique:
entrez:
23
7
2020
pubmed:
23
7
2020
medline:
20
5
2021
Statut:
ppublish
Résumé
To estimate incidence of newly diagnosed mental disorders among ICU patients. Retrospective-matched cohort study using a population-based administrative database. Manitoba, Canada. A total of 49,439 ICU patients admitted between 2000 and 2012 were compared with two control groups (hospitalized: n = 146,968 and general population: n = 141,937), matched on age (± 2 yr), sex, region of residence, and hospitalization year. None. Incident mental disorders (mood, anxiety, substance use, personality, posttraumatic stress disorder, schizophrenia, and psychotic disorders) not diagnosed during the 5-year period before the index ICU or hospital admission date (including matched general population group), but diagnosed during the subsequent 5-year period. Multivariable survival models adjusted for sociodemographic variables, Charlson comorbidity index, admission diagnostic category, and number of ICU and non-ICU exposures. ICU cohort had a 14.5% (95% CI, 14.0-15.0) and 42.7% (95% CI, 42.0-43.5) age- and sex-standardized incidence of any diagnosed mental disorder at 1 and 5 years post-ICU exposure, respectively. In multivariable analysis, ICU cohort had increased risk of any diagnosed mental disorder at all time points versus the hospitalized cohort (year 5: adjusted hazard ratio, 2.00; 95% CI, 1.80-2.23) and the general population cohort (year 5: adjusted hazard ratio, 3.52; 95% CI, 3.23-3.83). A newly diagnosed mental disorder was associated with younger age, female sex, more recent admitting years, presence of preexisting comorbidities, and repeat ICU admission. ICU admission is associated with an increased incidence of mood, anxiety, substance use, and personality disorders over a 5-year period.
Identifiants
pubmed: 32697508
doi: 10.1097/CCM.0000000000004413
pii: 00003246-202008000-00031
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e675-e683Subventions
Organisme : CIHR
ID : 333252
Pays : Canada
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