Glycopolymers for Efficient Inhibition of Galectin-3:
Journal
Biomacromolecules
ISSN: 1526-4602
Titre abrégé: Biomacromolecules
Pays: United States
ID NLM: 100892849
Informations de publication
Date de publication:
10 08 2020
10 08 2020
Historique:
pubmed:
23
7
2020
medline:
22
6
2021
entrez:
23
7
2020
Statut:
ppublish
Résumé
The development of efficient galectin-3 (Gal-3) inhibitors draws attention in the field of anti-cancer therapy, especially due to the prominent role of extra- and intracellular Gal-3 in vital processes of cancerogenesis, such as immunosuppression, stimulation of tumor cells proliferation, survival, invasion, apoptotic resistance, and metastasis formation and progression. Here, by combining poly-LacNAc (Galβ4GlcNAc)-derived oligosaccharides with
Identifiants
pubmed: 32697592
doi: 10.1021/acs.biomac.0c00515
doi:
Substances chimiques
Galectin 3
0
Polymers
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM