Goiter Prevalence and Thyroid Autoimmunity in School Children of Delhi.
Goiter
UIC
iodine deficiency
Journal
Indian journal of endocrinology and metabolism
ISSN: 2230-8210
Titre abrégé: Indian J Endocrinol Metab
Pays: India
ID NLM: 101555690
Informations de publication
Date de publication:
Historique:
received:
21
12
2019
revised:
30
12
2019
accepted:
26
01
2020
entrez:
24
7
2020
pubmed:
24
7
2020
medline:
24
7
2020
Statut:
ppublish
Résumé
Several studies from India, performed prior to 2010, have reported a goiter prevalence of greater than five per cent in school going children. There has been considerable success in universal salt iodization efforts in the past decade. We studied the prevalence of goiter and thyroid autoimmunity in school going children in Delhi between 2010 and 2014 to assess the impact of salt iodization. The study employed the population proportionate to size (PPS) cluster sampling methodology to select subjects between the age of six and 14 years, from all 34 wards of 9 districts of Delhi. Cluster randomization sampling design was followed and in this way we identified 30 wards, from each of which 90 children were recruited for the study. The total sample size was 2700 children. Estimation of fT3, fT4, TSH, anti-TPO antibodies and urine iodine concentration (UIC) was done for 10% of the study population. The prevalence of goiter in this study in the 6-14 years age group was 6.4%. The prevalence of goiter was higher in females (7.7% compared to 5.3% in males, There is improvement in goiter prevalence in the post-iodization period in Delhi. But still, residual goiter rates are above five per cent suggesting presence of other causes of goiter in this area. There is a high prevalence of thyroid autoimmunity in this population.
Identifiants
pubmed: 32699791
doi: 10.4103/ijem.IJEM_645_19
pii: IJEM-24-202
pmc: PMC7333756
doi:
Types de publication
Journal Article
Langues
eng
Pagination
202-205Informations de copyright
Copyright: © 2020 Indian Journal of Endocrinology and Metabolism.
Déclaration de conflit d'intérêts
There are no conflicts of interest.
Références
East Afr Med J. 1998 Mar;75(3):166-70
pubmed: 9640816
Exp Clin Endocrinol Diabetes. 1998;106 Suppl 3:S22-7
pubmed: 9865549
Clin Endocrinol (Oxf). 2003 Dec;59(6):672-81
pubmed: 14974907
Trop Med Int Health. 1996 Oct;1(5):723-9
pubmed: 8911460
Public Health Nutr. 2010 Mar;13(3):424-9
pubmed: 19519973
Indian J Pediatr. 2004 Mar;71(3):211-2
pubmed: 15080406
Indian Pediatr. 2008 Jun;45(6):469-74
pubmed: 18599931
Biol Trace Elem Res. 1999 Nov;70(2):127-36
pubmed: 10535522
Clin Endocrinol (Oxf). 2012 Jun;76(6):905-10
pubmed: 22142266
Indian J Med Res. 2011 Jan;133:103-9
pubmed: 21321427
Acta Endocrinol Suppl (Copenh). 1973 Oct;179:110
pubmed: 4523764
Public Health Nutr. 2018 Nov;21(16):3027-3036
pubmed: 30198480
Prog Clin Biol Res. 1988;280:349-63
pubmed: 2459720
Indian J Physiol Pharmacol. 2005 Jul-Sep;49(3):284-8
pubmed: 16440845
Indian J Med Res. 2018 Nov;148(5):503-510
pubmed: 30666977