Characteristics of Laryngeal Osteosarcoma: A Critical Review.
Larynx
Osteosarcoma
Radiotherapy
Sarcoma
Surgery
Journal
Oncology and therapy
ISSN: 2366-1089
Titre abrégé: Oncol Ther
Pays: New Zealand
ID NLM: 101677510
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
received:
13
01
2020
entrez:
24
7
2020
pubmed:
24
7
2020
medline:
24
7
2020
Statut:
ppublish
Résumé
Laryngeal sarcomas constitute an extremely rare entity among head and neck malignancies. Furthermore, most of them are chondrosarcomas, and the osteogenic form remains a true rarity. In general, there is a lack of information on the characteristics of laryngeal osteosarcoma. Thus, we sought to critically review the existing world literature on laryngeal osteosarcoma in order to develop a more accurate clinicopathological profile of this malignancy. Laryngeal osteosarcoma has a predilection for elderly male patients, as 87% were male in the present series and the mean age was 62 years (range 32-80), and without a direct association with tobacco exposure. Osteosarcoma of the larynx is typically a highly malignant neoplasm that metastasizes early, has a propensity for hematogenous spread and also has a marked tendency to recur. Twelve (41%) out of the 29 cases in the present review with follow-up data had metastatic disease. The aspects that distinguish osteosarcoma from its differential diagnostic alternatives are discussed in this review.
Identifiants
pubmed: 32700074
doi: 10.1007/s40487-020-00110-8
pii: 10.1007/s40487-020-00110-8
pmc: PMC7359981
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
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