Serum lipoprotein (a) associates with a higher risk of reduced renal function: a prospective investigation.
epidemiology.
hypertension
lipids
renal dysfunction
type 2 diabetes
Journal
Journal of lipid research
ISSN: 1539-7262
Titre abrégé: J Lipid Res
Pays: United States
ID NLM: 0376606
Informations de publication
Date de publication:
10 2020
10 2020
Historique:
pubmed:
25
7
2020
medline:
25
2
2023
entrez:
25
7
2020
Statut:
ppublish
Résumé
Lipoprotein (a) [Lp(a)] is a well-known risk factor for cardiovascular disease, but analysis on Lp(a) and renal dysfunction is scarce. We aimed to investigate prospectively the association of serum Lp(a) with the risk of reduced renal function, and further investigated whether diabetic or hypertensive status modified such association. Six thousand two hundred and fifty-seven Chinese adults aged ≤40 years and free of reduced renal function at baseline were included in the study. Reduced renal function was defined as estimated glomerular filtration rate <60 ml/min/1.73 m
Identifiants
pubmed: 32703886
pii: S0022-2275(20)43699-5
doi: 10.1194/jlr.RA120000771
pmc: PMC7529054
doi:
Substances chimiques
Lipoprotein(a)
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1320-1327Informations de copyright
Copyright © 2020 Xuan et al. Published by The American Society for Biochemistry and Molecular Biology, Inc.
Déclaration de conflit d'intérêts
Conflict of interest—The authors declare that they have no conflicts of interest with the contents of this article.
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