Plasma extracellular vesicle proteins are associated with stress-induced myocardial ischemia in women presenting with chest pain.
Aged
Biomarkers
Chest Pain
/ etiology
Computed Tomography Angiography
Extracellular Vesicles
/ metabolism
Female
Humans
Male
Middle Aged
Myocardial Ischemia
/ diagnosis
Positron Emission Tomography Computed Tomography
Proteins
/ metabolism
Proteome
Proteomics
/ methods
Risk Factors
Sex Factors
Stress, Physiological
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
23 07 2020
23 07 2020
Historique:
received:
30
03
2020
accepted:
12
06
2020
entrez:
25
7
2020
pubmed:
25
7
2020
medline:
22
12
2020
Statut:
epublish
Résumé
Diagnosing stable ischemic heart disease (IHD) is challenging, especially in females. Currently, no blood test is available. Plasma extracellular vesicles (EV) are emerging as potential biomarker source. We therefore aimed to identify stress induced ischemia due to stable IHD with plasma extracellular vesicle protein levels in chest pain patients. We analyzed 450 patients suspected for stable IHD who were referred for
Identifiants
pubmed: 32704130
doi: 10.1038/s41598-020-69297-0
pii: 10.1038/s41598-020-69297-0
pmc: PMC7378184
doi:
Substances chimiques
Biomarkers
0
Proteins
0
Proteome
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
12257Références
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