Drug Dosing in Critically Ill Patients with Acute Kidney Injury and on Renal Replacement Therapy.

Acute kidney injury Critically ill Drug dosing

Journal

Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine
ISSN: 0972-5229
Titre abrégé: Indian J Crit Care Med
Pays: India
ID NLM: 101208863

Informations de publication

Date de publication:
Apr 2020
Historique:
entrez: 25 7 2020
pubmed: 25 7 2020
medline: 25 7 2020
Statut: ppublish

Résumé

Acute kidney injury (AKI) complicates in around 40-50% of patients in intensive care units (ICUs), and this can account for up to 80% mortality, especially in those patients requiring renal replacement therapy (RRT). Appropriate drug dosing in such patients is a challenge to the intensivists due to various factors such as patient related (appropriate body weight, organ clearance, serum protein concentration), drug related [molecular weight (MW), protein binding, volume of distribution ( Saran S, Rao NS, Azim A. Drug Dosing in Critically Ill Patients with Acute Kidney Injury and on Renal Replacement Therapy. Indian J Crit Care Med 2020;24(Suppl 3):S129-S134.

Identifiants

pubmed: 32704220
doi: 10.5005/jp-journals-10071-23392
pmc: PMC7347056
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

S129-S134

Informations de copyright

Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd.

Déclaration de conflit d'intérêts

Source of support: Nil Conflict of interest: None

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Auteurs

Sai Saran (S)

Department of Critical Care Medicine, Super Speciality Cancer Institute and Hospital, Lucknow, Uttar Pradesh, India.

Namrata S Rao (NS)

Department of Nephrology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Afzal Azim (A)

Department of Critical Care Medicine, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Classifications MeSH