Impact of Clinical, Laboratory and Fluid Therapy Variables on Hospital Length of Stay for Children with Acute Pancreatitis.
Fluid therapy
Length of stay
Pancreatitis
Journal
Pediatric gastroenterology, hepatology & nutrition
ISSN: 2234-8646
Titre abrégé: Pediatr Gastroenterol Hepatol Nutr
Pays: Korea (South)
ID NLM: 101590471
Informations de publication
Date de publication:
Jul 2020
Jul 2020
Historique:
received:
16
11
2019
revised:
15
02
2020
accepted:
08
03
2020
entrez:
25
7
2020
pubmed:
25
7
2020
medline:
25
7
2020
Statut:
ppublish
Résumé
There have been many efforts to develop generalizable severity markers in children with acute pancreatitis (AP). Expert opinion panels have developed consensus guidelines on management but it is unclear if these are sufficient or valid. Our study aims to assess the effect of clinical and laboratory variables, in addition to treatment modality on hospital length of stay (LOS) as a proxy variable for severity in pediatric patients admitted with AP. We conducted a retrospective chart review of patients between ages of 0-18 years, who were admitted with AP at 2 institutions between 2013-2018, John R. Oishei Children's Hospital (Buffalo, NY, USA) and Medical University of South Carolina Children's Hospital (Charleston, SC, USA). We constructed three linear regression models to analyze the effect of clinical signs of organ dysfunction, laboratory markers and fluid intake on hospital LOS. Ninety-two patients were included in the study. The mean age was 12 years (range, 7.6-17.4 years), 55% were females, and median LOS was 3 days. The most frequent cause of AP was idiopathic. Our study showed that elevated blood urea nitrogen (BUN) on admission ( Elevated serum BUN on admission, persistent tachycardia and need for fluid resuscitation were associated with increase LOS in pediatric AP. Daily total fluid intake above recommended maintenance did not reduce LOS.
Identifiants
pubmed: 32704496
doi: 10.5223/pghn.2020.23.4.356
pmc: PMC7354873
doi:
Types de publication
Journal Article
Langues
eng
Pagination
356-365Informations de copyright
Copyright © 2020 by The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition.
Déclaration de conflit d'intérêts
Conflict of Interest: The authors have no financial conflicts of interest.
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