The Role of Epigenetic Dysregulation in Suicidal Behaviors.
DNA methylation
EWAS
Epigenetics
Suicidal behaviors
Suicide
Journal
Current topics in behavioral neurosciences
ISSN: 1866-3370
Titre abrégé: Curr Top Behav Neurosci
Pays: Germany
ID NLM: 101535383
Informations de publication
Date de publication:
2020
2020
Historique:
pubmed:
25
7
2020
medline:
29
12
2020
entrez:
25
7
2020
Statut:
ppublish
Résumé
Suicidal behaviors have been associated with both heritable genetic variables and environmental risk factors. Epigenetic processes, such as DNA methylation, have important roles in mediating the effects of the environment on behavior. Dysregulation of these processes has been observed in many psychiatric disorders, and evidence suggests that they may also be involved in suicidal behaviors. Herein, we have summarized candidate gene and epigenome-wide studies which have investigated DNA methylation in relation to suicidal behaviors, as well as discussed some of the limitations of the field to date.
Identifiants
pubmed: 32705498
doi: 10.1007/7854_2020_160
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
41-61Références
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