Genetic factors related to the immune system in subjects at risk of developing Alzheimer's disease.

Alzheimer Disease / genetics Genetic Predisposition to Disease / genetics Humans
Alzheimer's disease Genetic variants immune risk factors immunopathology

Journal

Journal of integrative neuroscience
ISSN: 0219-6352
Titre abrégé: J Integr Neurosci
Pays: Singapore
ID NLM: 101156357

Informations de publication

Date de publication:
30 Jun 2020
Historique:
received: 21 04 2020
accepted: 23 06 2020
entrez: 25 7 2020
pubmed: 25 7 2020
medline: 11 5 2021
Statut: ppublish

Résumé

Alzheimer's disease is the most common neurodegenerative disease and the cause of dementia. Although the pathomechanisms underlying Alzheimer's disease have not been fully elucidated, there is evidence that genetic and environmental factors contribute to its development. Immune system changes, both environmentally-induced and, as a result of predisposing genetics, are implicated in Alzheimer's disease etiopathogenesis. Genes associated with immune system dysfunction in Alzheimer's disease include

Identifiants

DOI: 10.31083/j.jin.2020.02.110 PMID: 32706201
pubmed: 32706201
pii: 1593409410598-1700119123
doi: 10.31083/j.jin.2020.02.110
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

359-371

Subventions

Organisme : United States
Pays : United States

Informations de copyright

© 2020 Prendecki et al. Published by IMR press.

Déclaration de conflit d'intérêts

The authors declare no competing interests.

Auteurs

Michał Prendecki (M)

Laboratory of Neurobiology, Department of Neurology, Poznan University of Medical Sciences, Poznan, 60355, Poland.

Marta Kowalska (M)

Laboratory of Neurobiology, Department of Neurology, Poznan University of Medical Sciences, Poznan, 60355, Poland.

Urszula Łagan-Jędrzejczyk (U)

Chair and Department of Neurology, Poznan University of Medical Sciences, Poznan, 60355, Poland.

Thomas Piekut (T)

Laboratory of Neurobiology, Department of Neurology, Poznan University of Medical Sciences, Poznan, 60355, Poland.

Aleksandra Krokos (A)

Laboratory of Neurobiology, Department of Neurology, Poznan University of Medical Sciences, Poznan, 60355, Poland.

Wojciech Kozubski (W)

Chair and Department of Neurology, Poznan University of Medical Sciences, Poznan, 60355, Poland.

Jolanta Dorszewska (J)

Laboratory of Neurobiology, Department of Neurology, Poznan University of Medical Sciences, Poznan, 60355, Poland.

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Classifications MeSH

questionsmedicales.fr › Troubles mentaux › Troubles neurocognitifs › Démence › Maladie d'Alzheimer › Genetic factors related to the immune system...
questionsmedicales.fr › Phénomènes génétiques › Génotype › Prédisposition génétique à une maladie › Genetic factors related to the immune system...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Genetic factors related to the immune system...