Impact of Eukaryotic Translation Initiation Factors on Breast Cancer: Still Much to Investigate.
breast carcinoma
eukaryotic initiation factors
translation initiation
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
21 Jul 2020
21 Jul 2020
Historique:
received:
01
06
2020
revised:
04
07
2020
accepted:
08
07
2020
entrez:
26
7
2020
pubmed:
28
7
2020
medline:
28
7
2020
Statut:
epublish
Résumé
Breast carcinoma (BC) remains one of the most serious health problems. It is a heterogeneous entity, and mainly classified according to receptor status for estrogen (ER), progesterone (PR) and egf (HER2/Neu), as well as the proliferation marker ki67. Gene expression in eukaryotes is regulated at the level of both gene transcription and translation, where eukaryotic initiation factors (eIFs) are key regulators of protein biosynthesis. Aberrant translation results in an altered cellular proteome, and this clearly effects cell growth supporting tumorigenesis. The relationship between various eIFs and BC entities, as well as the related regulatory mechanisms, has meanwhile become a focus of scientific interest. Here, we give an overview on the current research state of eIF function, focusing on BC.
Identifiants
pubmed: 32708122
pii: cancers12071984
doi: 10.3390/cancers12071984
pmc: PMC7409344
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
Front Med (Lausanne). 2018 Sep 04;5:248
pubmed: 30234119
Oncogene. 2015 Apr 16;34(16):2032-42
pubmed: 24909168
Cancer Biol Ther. 2009 Aug;8(15):1463-9
pubmed: 19483468
J Biol Chem. 2019 Feb 15;294(7):2267-2278
pubmed: 30573685
Updates Surg. 2017 Sep;69(3):313-317
pubmed: 28260181
J Biol Chem. 2013 Jun 28;288(26):18732-42
pubmed: 23667251
Int J Oncol. 2011 Nov;39(5):1337-45
pubmed: 21750861
Cancer Res. 2007 Jul 15;67(14):6814-24
pubmed: 17638893
Breast Cancer Res Treat. 2014 Nov;148(2):437-44
pubmed: 25257728
Cell Death Dis. 2016 Mar 10;7:e2138
pubmed: 26962688
Cancer Res. 2015 Mar 15;75(6):1102-12
pubmed: 25608710
Nat Chem Biol. 2011 Sep 25;7(11):787-93
pubmed: 21946274
Cancer Sci. 2012 Sep;103(9):1656-64
pubmed: 22632091
Nature. 2008 Oct 2;455(7213):684-8
pubmed: 18784653
EMBO J. 2000 Dec 1;19(23):6622-33
pubmed: 11101534
Science. 2006 Oct 20;314(5798):467-71
pubmed: 17053147
Br J Cancer. 2016 Jul 26;115(3):339-45
pubmed: 27280636
Nat Biotechnol. 2016 Apr;34(4):419-23
pubmed: 26928769
Arch Biochem Biophys. 2007 Sep 1;465(1):266-73
pubmed: 17601486
Clin Cancer Res. 2017 May 15;23(10):2575-2583
pubmed: 27986751
Nat Commun. 2016 May 10;7:11479
pubmed: 27161491
Clin Cancer Res. 2007 Jan 1;13(1):81-9
pubmed: 17200342
Cancer. 1997 Jun 15;79(12):2385-90
pubmed: 9191527
Cell Cycle. 2008 Aug;7(15):2346-51
pubmed: 18677106
Biochemistry. 2000 Oct 24;39(42):12929-38
pubmed: 11041858
Nat Med. 2004 May;10(5):484-6
pubmed: 15098029
Oncogene. 2013 Feb 14;32(7):861-71
pubmed: 22484424
Cancer Lett. 2013 Oct 28;340(1):9-21
pubmed: 23830805
Br J Cancer. 2009 May 5;100(9):1393-9
pubmed: 19367274
Oncogene. 2018 Feb 1;37(5):651-662
pubmed: 28991229
Proc Natl Acad Sci U S A. 2004 Dec 28;101(52):18105-10
pubmed: 15601771
Biochemistry. 2018 Oct 9;57(40):5910-5920
pubmed: 30211544
Nature. 2000 Aug 17;406(6797):747-52
pubmed: 10963602
Cancer Lett. 2013 May 28;332(2):249-64
pubmed: 20732741
Cancer Res. 2008 Feb 1;68(3):631-4
pubmed: 18245460
Blood. 2009 Jul 9;114(2):257-60
pubmed: 19433856
FEBS Lett. 2015 Jul 22;589(16):2110-6
pubmed: 26144282
Med Sci Monit. 2017 Aug 30;23:4182-4191
pubmed: 28854163
Mol Cell. 2017 Apr 20;66(2):194-205.e5
pubmed: 28392174
Oncotarget. 2017 Jan 10;8(2):2906-2915
pubmed: 27926520
Clin Cancer Res. 2011 May 1;17(9):2874-84
pubmed: 21415224
Microbiol Mol Biol Rev. 2002 Sep;66(3):460-85, table of contents
pubmed: 12209000
Breast Cancer Res Treat. 2010 Oct;123(3):725-31
pubmed: 20020197
Biochim Biophys Acta. 2009 Sep-Oct;1789(9-10):518-28
pubmed: 19631772
J Biol Chem. 1999 Jun 4;274(23):16487-93
pubmed: 10347211
Nat Cell Biol. 2009 Jul;11(7):903-8
pubmed: 19525934
J Biol Chem. 2008 Aug 29;283(35):24047-60
pubmed: 18544531
Exp Cell Res. 2018 Jul 15;368(2):236-247
pubmed: 29746817
Front Oncol. 2019 Dec 06;9:1311
pubmed: 31867270
Annu Rev Biochem. 1999;68:913-63
pubmed: 10872469
Nat Genet. 2014 Oct;46(10):1051-9
pubmed: 25151356
Clin Cancer Res. 2010 Oct 15;16(20):4914-20
pubmed: 20702611
J Surg Res. 2004 Jan;116(1):98-103
pubmed: 14732354
Nat Rev Drug Discov. 2011 Oct 31;10(11):868-80
pubmed: 22037041
Science. 2011 Nov 25;334(6059):1081-6
pubmed: 22116877
Int J Oncol. 2014 Jun;44(6):1980-8
pubmed: 24691491
Cancer Res. 2011 Jun 15;71(12):4068-73
pubmed: 21498638
Mol Cell Biol. 2015 Aug;35(15):2597-609
pubmed: 25986608
Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10869-74
pubmed: 11553815
Med Res Rev. 2012 Jul;32(4):786-814
pubmed: 22495651
Apoptosis. 2016 Oct;21(10):1106-24
pubmed: 27392939
Biomolecules. 2019 Sep 18;9(9):
pubmed: 31540491
Int J Oncol. 2001 Jan;18(1):175-9
pubmed: 11115556
Nature. 2010 May 20;465(7296):378-81
pubmed: 20485439
PLoS One. 2012;7(2):e32047
pubmed: 22348144
Cancer Res. 2008 Jul 1;68(13):5326-34
pubmed: 18593934
Cell Death Dis. 2015 Jan 22;6:e1603
pubmed: 25611378
Cancer Res. 2017 Aug 15;77(16):4268-4278
pubmed: 28646021
BMC Public Health. 2015 Jan 31;15:37
pubmed: 25636332
Cell. 2017 Jul 27;170(3):564-576.e16
pubmed: 28753430
Mol Cancer Res. 2015 Oct;13(10):1421-30
pubmed: 26056130
Sci Rep. 2017 Mar 15;7:44674
pubmed: 28294178
Biochem Cell Biol. 2008 Apr;86(2):178-83
pubmed: 18443631
Mol Cell Biol. 2004 Aug;24(15):6539-49
pubmed: 15254222
Curr Opin Oncol. 2013 Jan;25(1):76-84
pubmed: 23197193
Clin Cancer Res. 2004 Oct 15;10(20):6779-88
pubmed: 15501954
Nat Commun. 2019 May 13;10(1):2139
pubmed: 31086176
Cancer Cell. 2004 Jun;5(6):553-63
pubmed: 15193258
JAMA. 2015 Oct 20;314(15):1599-614
pubmed: 26501536
Cancer Prev Res (Phila). 2010 Mar;3(3):331-8
pubmed: 20145189
EMBO Rep. 2009 May;10(5):459-65
pubmed: 19373251
J Biol Chem. 1997 Nov 28;272(48):30314-21
pubmed: 9374518
Nucleic Acids Res. 2016 Sep 6;44(15):7441-56
pubmed: 27325746
Oncotarget. 2014 Jan 30;5(2):530-43
pubmed: 24504069
Cancer Discov. 2019 Feb;9(2):264-281
pubmed: 30305285
Nature. 2012 Apr 18;486(7403):346-52
pubmed: 22522925
Anticancer Res. 2017 Oct;37(10):5329-5341
pubmed: 28982841