Postoperative Morbidity and Failure to Rescue in Surgery for Gastric Cancer: A Single Center Retrospective Cohort Study of 1107 Patients from 1972 to 2014.
complications
failure to rescue
gastrectomy
gastric cancer
mortality
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
18 Jul 2020
18 Jul 2020
Historique:
received:
19
06
2020
revised:
15
07
2020
accepted:
16
07
2020
entrez:
26
7
2020
pubmed:
28
7
2020
medline:
28
7
2020
Statut:
epublish
Résumé
The aim of this study was to evaluate postoperative morbidity, mortality, and failure to rescue following complications after radical resection for gastric cancer. A retrospective analysis of the surgical database of patients with gastroesophageal malignancies at our institution was performed. All consecutive patients undergoing R0 gastrectomy for pT1-4 M0 gastric adenocarcinoma between October 1972 and February 2014 were eligible for this analysis. Patients were divided into two groups according to the date of surgery: an early cohort operated on from 1972-1992 and a late cohort operated on from 1993-2014. Both groups were compared regarding patient characteristics and surgical outcomes. A total of 1107 patients were included. Postoperative mortality was more than twice as high in patients operated on from 1972-1992 compared to patients operated on from 1993-2014 (6.8% vs. 3.2%, In the course of four decades, postoperative mortality after radical resection for gastric cancer has more than halved. In this cohort, the reason for this decrease was reduced mortality due to non-surgical complications. Major surgical morbidity after gastrectomy remains challenging.
Sections du résumé
BACKGROUND
BACKGROUND
The aim of this study was to evaluate postoperative morbidity, mortality, and failure to rescue following complications after radical resection for gastric cancer.
METHODS
METHODS
A retrospective analysis of the surgical database of patients with gastroesophageal malignancies at our institution was performed. All consecutive patients undergoing R0 gastrectomy for pT1-4 M0 gastric adenocarcinoma between October 1972 and February 2014 were eligible for this analysis. Patients were divided into two groups according to the date of surgery: an early cohort operated on from 1972-1992 and a late cohort operated on from 1993-2014. Both groups were compared regarding patient characteristics and surgical outcomes.
RESULTS
RESULTS
A total of 1107 patients were included. Postoperative mortality was more than twice as high in patients operated on from 1972-1992 compared to patients operated on from 1993-2014 (6.8% vs. 3.2%,
CONCLUSION
CONCLUSIONS
In the course of four decades, postoperative mortality after radical resection for gastric cancer has more than halved. In this cohort, the reason for this decrease was reduced mortality due to non-surgical complications. Major surgical morbidity after gastrectomy remains challenging.
Identifiants
pubmed: 32708438
pii: cancers12071953
doi: 10.3390/cancers12071953
pmc: PMC7409077
pii:
doi:
Types de publication
Journal Article
Langues
eng
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