Risk-Reducing Gynecological Surgery in Lynch Syndrome: Results of an International Survey from the Prospective Lynch Syndrome Database.

Lynch syndrome endometrial cancer ovarian cancer risk-reducing surgery

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
18 Jul 2020
Historique:
received: 25 05 2020
revised: 05 07 2020
accepted: 08 07 2020
entrez: 26 7 2020
pubmed: 28 7 2020
medline: 28 7 2020
Statut: epublish

Résumé

To survey risk-reducing hysterectomy and bilateral salpingo-oophorectomy (BSO) practice and advice regarding hormone replacement therapy (HRT) in women with Lynch syndrome. We conducted a survey in 31 contributing centers from the Prospective Lynch Syndrome Database (PLSD), which incorporates 18 countries worldwide. The survey covered local policies for risk-reducing hysterectomy and BSO in Lynch syndrome, the timing when these measures are offered, the involvement of stakeholders and advice regarding HRT. Risk-reducing hysterectomy and BSO are offered to Most centers offer risk-reducing gynecological surgery to carriers of

Identifiants

pubmed: 32708519
pii: jcm9072290
doi: 10.3390/jcm9072290
pmc: PMC7408942
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Department of Health
ID : NIHR-CS-012-009
Pays : United Kingdom
Organisme : Centro de Investigación Biomédica en Red de Cáncer
ID : grant 2017SGR1282
Organisme : Manchester Biomedical Research Centre
ID : IS-BRC-1215-20007
Organisme : KWF Kankerbestrijding
ID : UL 2017-8223
Organisme : Kreftforeningen
ID : contract 194751-2017
Organisme : Federación Española de Enfermedades Raras
ID : SAF2015-68016-
Organisme : Medical Research Council
ID : MR/M018431/1
Pays : United Kingdom

Références

JAMA. 2002 Aug 21;288(7):872-81
pubmed: 12186605
Best Pract Res Clin Obstet Gynaecol. 2020 May;65:46-65
pubmed: 32192936
J Clin Oncol. 2018 Oct 10;36(29):2961-2968
pubmed: 30161022
Genet Med. 2020 Jan;22(1):15-25
pubmed: 31337882
JAMA. 2002 Jul 17;288(3):321-33
pubmed: 12117397
Climacteric. 2015;18(4):483-91
pubmed: 25845383
Cochrane Database Syst Rev. 2019 Aug 28;8:CD012858
pubmed: 31456223
Gut. 2017 Mar;66(3):464-472
pubmed: 26657901
Gastroenterology. 2000 May;118(5):829-34
pubmed: 10784581
Gut. 2018 Jul;67(7):1306-1316
pubmed: 28754778
Int J Cancer. 2012 Jan 15;130(2):419-30
pubmed: 21365647
Am J Med. 1999 May;106(5):574-82
pubmed: 10335731
BJOG. 2020 Jul 29;:
pubmed: 32725920
JAMA Oncol. 2017 Dec 1;3(12):1702-1706
pubmed: 28772289
Cancer Epidemiol Biomarkers Prev. 2000 Apr;9(4):443-7
pubmed: 10794491
Lancet Oncol. 2008 Apr;9(4):385-91
pubmed: 18374292
N Engl J Med. 2020 Jan 30;382(5):446-455
pubmed: 31995690
Genet Med. 2019 Oct;21(10):2390-2400
pubmed: 30918358
N Engl J Med. 2006 Jan 19;354(3):261-9
pubmed: 16421367
Adv Ther. 2018 Apr;35(4):577-589
pubmed: 29516408
Gynecol Obstet Fertil Senol. 2019 Jun;47(6):497-503
pubmed: 31003015
Obstet Gynecol. 1999 May;93(5 Pt 2):880-8
pubmed: 10912438

Auteurs

Mev Dominguez-Valentin (M)

Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, Part of Oslo University Hospital, 0379 Oslo, Norway.

Toni T Seppälä (TT)

Department of Abdominal Surgery, Helsinki University Central Hospital, 00029 Helsinki, Finland.
Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.

Christoph Engel (C)

Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, 04107 Leipzig, Germany.

Stefan Aretz (S)

Institute of Human Genetics, University of Bonn, 53127 Bonn, Germany.
Center for Hereditary Tumor Syndromes, University Hospital Bonn, 53127 Bonn, Germany.

Finlay Macrae (F)

Colorectal Medicine and Genetics, The Royal Melbourne Hospital, 3052 Melbourne, Australia.
Department of Medicine, University of Melbourne, 3052 Melbourne, Australia.

Ingrid Winship (I)

Colorectal Medicine and Genetics, The Royal Melbourne Hospital, 3052 Melbourne, Australia.
Department of Medicine, University of Melbourne, 3052 Melbourne, Australia.

Gabriel Capella (G)

Hereditary Cancer Program, Catalan Institute of Oncology, Insititut d'Investigació Biomèdica de Bellvitge (IDIBELL), ONCOBELL Program, L'Hospitalet de Llobregat, 08908 Barcelona, Spain.
Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), 28029 Madrid, Spain.

Huw Thomas (H)

Department of Surgery and Cancer, St Mark's Hospital, Imperial College London, London HA1 3UJ, UK.

Eivind Hovig (E)

Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, Part of Oslo University Hospital, 0379 Oslo, Norway.
Center for Bioinformatics, Department of Informatics, University of Oslo, 0316 Oslo, Norway.

Maartje Nielsen (M)

Leids Universitair Medisch Centrum, Department of Clinical Genetics, 2300RC Leiden, The Netherlands.

Rolf H Sijmons (RH)

Department of Genetics, University of Groningen, University Medical Center Groningen, 9713GZ Groningen, The Netherlands.

Lucio Bertario (L)

Scientific Consultant of the Division of Prevention and Genetic Oncology, European Institute of Oncology, Fondazione IRCCS Isrtituto nazionale dei Tumori, 20141 Milan, Italy.

Bernardo Bonanni (B)

Division of Prevention and Genetic Oncology, European Institute of Oncology, 20141 Milan, Italy.

Maria Grazia Tibiletti (MG)

Ospedale di Circolo ASST Settelaghi, Centro di Ricerca Tumori Eredo-Familiari, Università dell'Insubria, 21100 Varese, Italy.

Giulia Martina Cavestro (GM)

Gastroenterology and Gastrointestinal Endoscopy Unit, Vita-Salute San Raffaele University, San Raffaele Scientific Institute, 20132 Milan, Italy.

Miriam Mints (M)

Karolinska Institutet, 171 76 Stockholm, Sweden.

Nathan Gluck (N)

Department of Gastroenterology, Tel-Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel-Aviv University, 64239 Tel Aviv, Israel.

Lior Katz (L)

Department of Gastroenterology and Hepatology, Hadassah Medical Center, 91120 Jerusalem, Israel.

Karl Heinimann (K)

Medical Genetics, Institute for Medical Genetics and Pathology, University Hospital Basel, 4031 Basel, Switzerland.

Carlos A Vaccaro (CA)

Hereditary Cancer Program (PROCANHE) Hospital Italiano de Buenos Aires, C1199ABB Ciudad Autónoma de Buenos Aires, Argentina.

Kate Green (K)

University of Manchester & Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.

Fiona Lalloo (F)

University of Manchester & Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.

James Hill (J)

Department of Surgery, Manchester University NHS Foundation Trust and University of Manchester, Manchester M13 9WL, UK.

Wolff Schmiegel (W)

Department of Medicine, Knappschaftskrankenhaus, Ruhr-University Bochum, 44801 Bochum, Germany.

Deepak Vangala (D)

Department of Medicine, Knappschaftskrankenhaus, Ruhr-University Bochum, 44892 Bochum, Germany.

Claudia Perne (C)

Institute of Human Genetics, University of Bonn, 53127 Bonn, Germany.
Center for Hereditary Tumor Syndromes, University Hospital Bonn, 53127 Bonn, Germany.

Hans-Georg Strauß (HG)

Department of Gynecology, University Clinics, Martin-Luther University, D-06097 Halle (Saale), Germany.

Johanna Tecklenburg (J)

Institute of Human Genetics, Hannover Medical School, 30625 Hannover, Germany.

Elke Holinski-Feder (E)

Medizinische Klinik und Poliklinik IV, Campus Innenstadt, Klinikum der Universität München, 80336 Munich, Germany.
MGZ-Medical Genetics Center, 80335 Munich, Germany.

Verena Steinke-Lange (V)

Medizinische Klinik und Poliklinik IV, Campus Innenstadt, Klinikum der Universität München, 80336 Munich, Germany.
MGZ-Medical Genetics Center, 80335 Munich, Germany.

Jukka-Pekka Mecklin (JP)

Faculty of Sport and Health Sciences, University of Jyväskylä, 40014 Jyväskylä, Finland.
Department of Surgery, Central Finland Health Care District, 40620 Jyväskylä, Finland.

John-Paul Plazzer (JP)

Colorectal Medicine and Genetics, The Royal Melbourne Hospital, 3052 Melbourne, Australia.

Marta Pineda (M)

Hereditary Cancer Program, Catalan Institute of Oncology, Insititut d'Investigació Biomèdica de Bellvitge (IDIBELL), ONCOBELL Program, L'Hospitalet de Llobregat, 08908 Barcelona, Spain.
Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), 28029 Madrid, Spain.

Matilde Navarro (M)

Hereditary Cancer Program, Catalan Institute of Oncology, Insititut d'Investigació Biomèdica de Bellvitge (IDIBELL), ONCOBELL Program, L'Hospitalet de Llobregat, 08908 Barcelona, Spain.
Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), 28029 Madrid, Spain.

Joan Brunet Vidal (JB)

Hereditary Cancer Program, Catalan Institute of Oncology, Insititut d'Investigació Biomèdica de Bellvitge (IDIBELL), ONCOBELL Program, L'Hospitalet de Llobregat, 08908 Barcelona, Spain.
Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), 28029 Madrid, Spain.

Revital Kariv (R)

Department of Gastroenterology, Tel-Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel-Aviv University, 64239 Tel Aviv, Israel.

Guy Rosner (G)

Department of Gastroenterology, Tel-Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel-Aviv University, 64239 Tel Aviv, Israel.

Tamara Alejandra Piñero (TA)

Hereditary Cancer Program (PROCANHE) Hospital Italiano de Buenos Aires, C1199ABB Ciudad Autónoma de Buenos Aires, Argentina.

María Laura Gonzalez (ML)

Hereditary Cancer Program (PROCANHE) Hospital Italiano de Buenos Aires, C1199ABB Ciudad Autónoma de Buenos Aires, Argentina.

Pablo Kalfayan (P)

Hereditary Cancer Program (PROCANHE) Hospital Italiano de Buenos Aires, C1199ABB Ciudad Autónoma de Buenos Aires, Argentina.

Julian R Sampson (JR)

Institute of Medical Genetics, Division of Cancer and Genetics, Cardiff University School of Medicine, Cardiff CF14 4XN, UK.

Neil A J Ryan (NAJ)

University of Manchester & Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.

D Gareth Evans (DG)

University of Manchester & Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.

Pål Møller (P)

Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, Part of Oslo University Hospital, 0379 Oslo, Norway.

Emma J Crosbie (EJ)

University of Manchester & Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.

Classifications MeSH