Tele-Monitoring of Cancer Patients' Rhythms during Daily Life Identifies Actionable Determinants of Circadian and Sleep Disruption.

age biomarkers circadian regulation circadian rhythms cortisol gastro-intestinal cancer melatonin patient-reported outcome measures sex sleep

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
17 Jul 2020
Historique:
received: 30 06 2020
revised: 13 07 2020
accepted: 14 07 2020
entrez: 26 7 2020
pubmed: 28 7 2020
medline: 28 7 2020
Statut: epublish

Résumé

The dichotomy index (I < O), a quantitative estimate of the circadian regulation of daytime activity and sleep, predicted overall cancer survival and emergency hospitalization, supporting its integration in a mHealth platform. Modifiable causes of I < O deterioration below 97.5%-(I < O)

Identifiants

pubmed: 32708950
pii: cancers12071938
doi: 10.3390/cancers12071938
pmc: PMC7409071
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Medical Research Council
ID : MR/M013170/1
Pays : United Kingdom
Organisme : University of Warwick
ID : NA
Organisme : philips respironics
ID : NA

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Auteurs

Francis Lévi (F)

Cancer Chronotherapy Team, Warwick Medical School, Coventry CV4 7AL, UK.
European Laboratory U935, Institut National de la Santé et de la Recherche Médicale (INSERM), Paris-Saclay University, 94801 Villejuif, France.
Hepato-Biliary Centre, Paul Brousse Hospital, Assistance Publique Hôpitaux de Paris (AP-HP), 94800 Villejuif, France.

Sandra Komarzynski (S)

Cancer Chronotherapy Team, Warwick Medical School, Coventry CV4 7AL, UK.
European Laboratory U935, Institut National de la Santé et de la Recherche Médicale (INSERM), Paris-Saclay University, 94801 Villejuif, France.

Qi Huang (Q)

Cancer Chronotherapy Team, Warwick Medical School, Coventry CV4 7AL, UK.
Department of Statistics, University of Warwick, Coventry CV4 7AL, UK.

Teresa Young (T)

Mount Vernon Cancer Centre, East and North Hertfordshire NHS Trust, Northwood, Middlesex HA6 2RN, UK.

Yeng Ang (Y)

Salford Royal NHS Foundation Trust, Salford M6 8HD, UK.
Gastrointestinal Sciences, Division of Diabetes, Endocrinology and Gastroenterology, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK.

Claire Fuller (C)

North Wales Cancer Treatment Centre, Ysbyty Gwynedd, Betsi Cadwaladr University Health Board, Bangor LL57 2PW, UK.

Matei Bolborea (M)

Cancer Chronotherapy Team, Warwick Medical School, Coventry CV4 7AL, UK.

Julia Brettschneider (J)

Department of Statistics, University of Warwick, Coventry CV4 7AL, UK.

Joanna Fursse (J)

Cancer Chronotherapy Team, Warwick Medical School, Coventry CV4 7AL, UK.

Bärbel Finkenstädt (B)

European Laboratory U935, Institut National de la Santé et de la Recherche Médicale (INSERM), Paris-Saclay University, 94801 Villejuif, France.
Department of Statistics, University of Warwick, Coventry CV4 7AL, UK.

David Pollard White (DP)

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02130, USA.
Philips Respironics, Murrysville, PA 15668, USA.

Pasquale Innominato (P)

Cancer Chronotherapy Team, Warwick Medical School, Coventry CV4 7AL, UK.
European Laboratory U935, Institut National de la Santé et de la Recherche Médicale (INSERM), Paris-Saclay University, 94801 Villejuif, France.
North Wales Cancer Treatment Centre, Ysbyty Gwynedd, Betsi Cadwaladr University Health Board, Bangor LL57 2PW, UK.

Classifications MeSH