Urinary ferritin; a potential noninvasive way to screen NICU patients for iron deficiency.
Journal
Journal of perinatology : official journal of the California Perinatal Association
ISSN: 1476-5543
Titre abrégé: J Perinatol
Pays: United States
ID NLM: 8501884
Informations de publication
Date de publication:
06 2021
06 2021
Historique:
received:
12
05
2020
accepted:
17
07
2020
revised:
23
06
2020
pubmed:
28
7
2020
medline:
9
10
2021
entrez:
26
7
2020
Statut:
ppublish
Résumé
Building on our previous study, showing a correlation between ferritin in serum and urine, we conducted a feasibility evaluation, measuring urinary ferritin as a potential noninvasive screening test for iron deficiency among NICU patients. This was a prospective analysis of paired serum/urine ferritin levels. We defined iron-limited erythropoiesis by a RET-He <5th percentile lower reference interval (<28 pg). We obtained 49 paired serum/urine samples from neonates judged as at-risk for iron deficiency. Urine ferritin ("corrected" for urine creatinine and specific gravity) correlated with serum ferritin (correlation coefficient of log Measuring urinary ferritin in NICU patients is feasible. Since low values identify iron-limitation, this could become a useful noninvasive screen.
Identifiants
pubmed: 32709979
doi: 10.1038/s41372-020-0746-6
pii: 10.1038/s41372-020-0746-6
doi:
Substances chimiques
Ferritins
9007-73-2
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1419-1425Subventions
Organisme : NIDDK NIH HHS
ID : U54 DK110858
Pays : United States
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