Pregnancy induced Cushing's syndrome and primary aldosteronism: a case report.
Cushing’s syndrome
Metyrapone
Preeclampsia
Pregnancy
Primary aldosteronism
Spironolactone
Journal
BMC pregnancy and childbirth
ISSN: 1471-2393
Titre abrégé: BMC Pregnancy Childbirth
Pays: England
ID NLM: 100967799
Informations de publication
Date de publication:
25 Jul 2020
25 Jul 2020
Historique:
received:
13
07
2019
accepted:
16
07
2020
entrez:
27
7
2020
pubmed:
28
7
2020
medline:
18
5
2021
Statut:
epublish
Résumé
First manifestation of Cushing's syndrome during pregnancy is rare. The diagnosis of both Cushing's and primary aldosteronism within a pregnancy has not been previously documented. Diagnosis is especially challenging due to the normal physiological changes that occur during pregnancy. Consequently, many tests that are normally used for diagnosis are not reliable. Tumor based etiologies can be surgically removed. Etiologies that are not tumor based are challenging to treat during pregnancy. A 25 year old G1P0 was admitted in the 22 Early diagnosis of pregnancy induced Cushing's syndrome and primary aldosteronism requires an interdisciplinary approach. Late detection has been associated with increased perinatal morbidity and mortality including but not limited to placental abruption and intrauterine demise. Collaboration is essential in the optimization of maternal and fetal outcomes.
Sections du résumé
BACKGROUND
BACKGROUND
First manifestation of Cushing's syndrome during pregnancy is rare. The diagnosis of both Cushing's and primary aldosteronism within a pregnancy has not been previously documented. Diagnosis is especially challenging due to the normal physiological changes that occur during pregnancy. Consequently, many tests that are normally used for diagnosis are not reliable. Tumor based etiologies can be surgically removed. Etiologies that are not tumor based are challenging to treat during pregnancy.
CASE PRESENTATION
METHODS
A 25 year old G1P0 was admitted in the 22
CONCLUSIONS
CONCLUSIONS
Early diagnosis of pregnancy induced Cushing's syndrome and primary aldosteronism requires an interdisciplinary approach. Late detection has been associated with increased perinatal morbidity and mortality including but not limited to placental abruption and intrauterine demise. Collaboration is essential in the optimization of maternal and fetal outcomes.
Identifiants
pubmed: 32711486
doi: 10.1186/s12884-020-03117-1
pii: 10.1186/s12884-020-03117-1
pmc: PMC7382848
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
421Références
Clin Endocrinol (Oxf). 1993 Sep;39(3):375-9
pubmed: 8222300
J Am Acad Dermatol. 2019 Apr;80(4):1147-1148
pubmed: 30352280
Clin Endocrinol (Oxf). 2015 Dec;83(6):774-8
pubmed: 26173372
Eur J Endocrinol. 2015 Jan;172(1):R23-30
pubmed: 25163723
Eur J Endocrinol. 2018 Jun;178(6):R259-R266
pubmed: 29523633
J Endocrinol Invest. 2006 Feb;29(2):164-7
pubmed: 16610244
Endocrine. 2017 Feb;55(2):555-563
pubmed: 27704478
Eur J Obstet Gynecol Reprod Biol. 2013 May;168(1):1-6
pubmed: 23305861
Invest Urol. 1975 Sep;13(2):95-6
pubmed: 1184344
BJOG. 2000 Jun;107(6):810-2
pubmed: 10847243
Eur J Endocrinol. 2017 Nov;177(5):K13-K20
pubmed: 28819015