Altered thiol/disulfide homeostasis and ischemia-modified albumin levels in children with irritable bowel syndrome.
irritable bowel syndrome
oxidative stress
thiol
Journal
Pediatrics international : official journal of the Japan Pediatric Society
ISSN: 1442-200X
Titre abrégé: Pediatr Int
Pays: Australia
ID NLM: 100886002
Informations de publication
Date de publication:
Mar 2021
Mar 2021
Historique:
revised:
08
07
2020
received:
22
05
2020
accepted:
20
07
2020
pubmed:
28
7
2020
medline:
19
8
2021
entrez:
27
7
2020
Statut:
ppublish
Résumé
In this study, we assessed thiol/disulfide homeostasis (TDH) parameters and ischemia-modified albumin (IMA) levels in children with irritable bowel syndrome (IBS) compared with healthy children. Fifty-six children with IBS and 53 healthy children were included in the study after assessment of inclusion and exclusion criteria. Plasma thiol/disulfide and IMA levels were compared between children with and without IBS. The mean values of native thiol, total thiol, and disulfide were 343.779 Impaired thiol/disulfide homeostasis and increased IMA levels can be considered etiological factors in children with IBS.
Sections du résumé
BACKGROUND
BACKGROUND
In this study, we assessed thiol/disulfide homeostasis (TDH) parameters and ischemia-modified albumin (IMA) levels in children with irritable bowel syndrome (IBS) compared with healthy children.
METHODS
METHODS
Fifty-six children with IBS and 53 healthy children were included in the study after assessment of inclusion and exclusion criteria. Plasma thiol/disulfide and IMA levels were compared between children with and without IBS.
RESULTS
RESULTS
The mean values of native thiol, total thiol, and disulfide were 343.779
CONCLUSION
CONCLUSIONS
Impaired thiol/disulfide homeostasis and increased IMA levels can be considered etiological factors in children with IBS.
Substances chimiques
Biomarkers
0
Disulfides
0
Serum Albumin
0
Sulfhydryl Compounds
0
ischemia-modified albumin
0
Serum Albumin, Human
ZIF514RVZR
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
300-305Informations de copyright
© 2020 Japan Pediatric Society.
Références
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