Preliminary Study of Right Ventricular Dyssynchrony Under High-Altitude Exposure: Determinants and Impacts.
high altitude
hypoxemia
pulmonary artery pressure
right ventricular dyssynchrony
speckle-tracking echocardiography
Journal
Frontiers in physiology
ISSN: 1664-042X
Titre abrégé: Front Physiol
Pays: Switzerland
ID NLM: 101549006
Informations de publication
Date de publication:
2020
2020
Historique:
received:
15
10
2019
accepted:
28
05
2020
entrez:
28
7
2020
pubmed:
28
7
2020
medline:
28
7
2020
Statut:
epublish
Résumé
The aims of this study were to explore the effect of high-altitude (HA) exposure on the incidence, determinants, and impacts of right ventricular dyssynchrony (RVD). In our study, 108 healthy young men were enrolled, and physiological and echocardiographic variables were recorded at both sea level and 4,100 m. By using two-dimensional speckle-tracking echocardiography, RVD was evaluated by calculating the R-R interval-corrected standard deviation of the time-to-peak systolic strain for the four mid-basal RV segments (RVSD4) and defined by RVSD4 > 18.7 ms. After HA exposure, RVSD4 was significantly increased, and the incidence of RVD was approximately 32.4%. Subjects with RVD showed lower oxygen saturation (SaO
Identifiants
pubmed: 32714205
doi: 10.3389/fphys.2020.00703
pmc: PMC7343894
doi:
Types de publication
Journal Article
Langues
eng
Pagination
703Informations de copyright
Copyright © 2020 Yang, Liu, Tian, Ding, Yu, Bian, Yang, Qin, Zhang, Ke, Yuan, Zhang, Rao and Huang.
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