Treatment Efficacy of Chuang Ling Ye, a Traditional Chinese Herbal Medicine Compound, on Idiopathic Granulomatous Mastitis: A Randomized Controlled Trial.


Journal

Evidence-based complementary and alternative medicine : eCAM
ISSN: 1741-427X
Titre abrégé: Evid Based Complement Alternat Med
Pays: United States
ID NLM: 101215021

Informations de publication

Date de publication:
2020
Historique:
received: 24 02 2020
accepted: 26 05 2020
entrez: 28 7 2020
pubmed: 28 7 2020
medline: 28 7 2020
Statut: epublish

Résumé

To explore whether Chuang Ling Ye (CLY), a traditional Chinese herbal medicine compound, could improve the treatment of idiopathic granulomatous mastitis (IGM) via decreasing inflammatory response. Herein, 40 patients with IGM who had wounds requiring dressing change were enrolled and randomly divided into two groups: the CLY group and the control group. The size of the neoplasm and pain score of patients were followed-up for 4 weeks. Local tissues were taken during dressing change and examined by commercial enzyme-linked immunosorbent assay (ELISA) kits. The levels of inflammatory markers, including interleukin-1 After treatment, the size of the neoplasm in the CLY group was significantly smaller than that in the control group (14.28 cm ± 8.96 cm vs. 21.14 cm ± 0.12 cm, External use of CLY could reduce the neoplasm of IGM by inhibiting local inflammation. This trial is registered with ChiCTR1800017744.

Identifiants

pubmed: 32714413
doi: 10.1155/2020/6964801
pmc: PMC7341429
doi:

Types de publication

Journal Article

Langues

eng

Pagination

6964801

Informations de copyright

Copyright © 2020 Jing-xian Xue et al.

Déclaration de conflit d'intérêts

The authors declare that there are no conflicts of interest regarding the publication of this manuscript.

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Auteurs

Jing-Xian Xue (JX)

Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.

Bei Ye (B)

Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.

Shun Liu (S)

Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.

Si-Han Cao (SH)

Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.

Wei-He Bian (WH)

Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.

Chang Yao (C)

Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.

Classifications MeSH