Glucocorticoids in pregnancy.
Addison’s disease
Cushing’s disease
Glucocorticoids
congenital adrenal hyperplasia
lung maturation
pregnancy
steroids
Journal
Obstetric medicine
ISSN: 1753-495X
Titre abrégé: Obstet Med
Pays: England
ID NLM: 101464191
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
received:
27
11
2018
accepted:
08
04
2019
entrez:
28
7
2020
pubmed:
28
7
2020
medline:
28
7
2020
Statut:
ppublish
Résumé
The physiological changes that occur during pregnancy include altered regulation of the hypothalamo-pituitary-adrenal axis. The fetoplacental unit plays a major role in this, together with alteration of circulating cortisol-binding globulin levels, with a net effect to increase both total and free cortisol levels. Importantly, there are several pathological conditions that require steroid treatment or replacement during pregnancy, and optimizing therapy is clearly crucial. The potential for acute and chronic adverse effects that can impact upon both the mother and the fetus makes the decision of how and when to instigate steroid therapy particularly challenging. In this review, we describe the physio-pathological changes to the hypothalamo-pituitary-adrenal axis that occur during pregnancy, tools to assess endogenous glucocorticoid reserve as well as discuss treatment strategies and the potential for the development of adverse events.
Identifiants
pubmed: 32714437
doi: 10.1177/1753495X19847832
pii: 10.1177_1753495X19847832
pmc: PMC7359660
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
62-69Informations de copyright
© The Author(s) 2019.
Références
Front Pharmacol. 2018 Sep 12;9:1027
pubmed: 30258364
Afr Health Sci. 2015 Dec;15(4):1074-80
pubmed: 26958006
Cochrane Database Syst Rev. 2017 Mar 21;3:CD004454
pubmed: 28321847
Lancet Diabetes Endocrinol. 2015 Mar;3(3):216-26
pubmed: 25098712
Eur J Endocrinol. 2017 Apr;176(4):R167-R181
pubmed: 28115464
J Clin Pharmacol. 2018 Sep;58(9):1223-1232
pubmed: 29733485
Lancet. 2000 May 13;355(9216):1692
pubmed: 10905246
Nat Rev Endocrinol. 2014 Jul;10(7):391-402
pubmed: 24863382
J Allergy Clin Immunol. 2015 Dec;136(6):1496-1502.e7
pubmed: 26220526
J Clin Endocrinol Metab. 2012 Jun;97(6):1881-3
pubmed: 22466333
Indian J Pediatr. 2014 May;81(5):466-72
pubmed: 24682835
Mol Cell Endocrinol. 1994 Nov;105(2):R11-7
pubmed: 7859916
JAMA. 1995 Feb 1;273(5):413-8
pubmed: 7823388
BMC Endocr Disord. 2016 Jun 17;16(1):36
pubmed: 27316460
Vitam Horm. 1999;57:249-324
pubmed: 10232052
J Clin Endocrinol Metab. 2010 Sep;95(9):4133-60
pubmed: 20823466
Endocr Rev. 2004 Oct;25(5):831-66
pubmed: 15466942
BJOG. 2018 May;125(6):719-727
pubmed: 28872770
Hua Xi Kou Qiang Yi Xue Za Zhi. 2018 Feb 1;36(1):9-16
pubmed: 29594989
Lancet. 2014 Jun 21;383(9935):2152-67
pubmed: 24503135
J Clin Endocrinol Metab. 2006 Oct;91(10):3866-72
pubmed: 16895954
J Clin Endocrinol Metab. 2003 Oct;88(10):5033-8
pubmed: 14557491
J Clin Endocrinol Metab. 2008 May;93(5):1526-40
pubmed: 18334580
Lancet. 2005 May 28-Jun 3;365(9474):1856-62
pubmed: 15924982
J Clin Endocrinol Metab. 1991 Nov;73(5):969-74
pubmed: 1939534
Clin Endocrinol (Oxf). 2018 Nov;89(5):577-585
pubmed: 30086199
Cochrane Database Syst Rev. 2015 Jul 05;(7):CD003935
pubmed: 26142898
Aust Fam Physician. 2016 Apr;45(4):206-7
pubmed: 27052137
J Endocr Soc. 2017 Jan 12;1(1):57-71
pubmed: 29264446
Lancet. 2017 Nov 11;390(10108):2194-2210
pubmed: 28576284
Curr Top Dev Biol. 2017;125:147-170
pubmed: 28527570
Obstet Med. 2014 Mar;7(1):45-7
pubmed: 27512421
Eur J Endocrinol. 2017 Nov;177(5):K13-K20
pubmed: 28819015
J Clin Endocrinol Metab. 2014 Jan;99(1):111-8
pubmed: 24170102
Clin Endocrinol (Oxf). 2013 Apr;78(4):497-502
pubmed: 23153216
Teratology. 2000 Dec;62(6):385-92
pubmed: 11091360
Eur J Endocrinol. 2004 Nov;151 Suppl 3:U63-9
pubmed: 15554888
J Clin Endocrinol Metab. 2018 Nov 1;103(11):4043-4088
pubmed: 30272171
Rheum Dis Clin North Am. 2017 Aug;43(3):489-502
pubmed: 28711148
Lancet Diabetes Endocrinol. 2016 Jul;4(7):611-29
pubmed: 27177728
Eur J Endocrinol. 2013 Oct 21;169(6):R165-75
pubmed: 24031090
Pediatr Endocrinol Rev. 2017 Sep;15(1):21-25
pubmed: 28845624
Eur J Endocrinol. 2018 Feb;178(2):R45-R53
pubmed: 29191934
J Clin Endocrinol Metab. 2018 Aug 1;103(8):3050-3059
pubmed: 29846658
Eur J Endocrinol. 2018 Jun;178(6):R259-R266
pubmed: 29523633
Pituitary. 2016 Feb;19(1):30-8
pubmed: 26346684
J Obstet Gynaecol. 2015 Jan;35(1):94-6
pubmed: 25029094
Am J Obstet Gynecol. 1976 Jan 1;124(1):43-50
pubmed: 1244745
Clin Endocrinol (Oxf). 2010 Oct;73(4):436-44
pubmed: 20550539
Cochrane Database Syst Rev. 2006 Jul 19;(3):CD004454
pubmed: 16856047
Endocr Rev. 2015 Aug;36(4):385-486
pubmed: 26067718
Br J Obstet Gynaecol. 1990 Jan;97(1):11-25
pubmed: 2137711
J Clin Endocrinol Metab. 2011 May;96(5):1533-40
pubmed: 21367926
J Pediatr. 1985 Jun;106(6):1008-11
pubmed: 3998938
J Matern Fetal Neonatal Med. 2017 Feb;30(3):284-293
pubmed: 27018008
Reprod Sci. 2009 Jan;16(1):94-104
pubmed: 18997118
J Clin Endocrinol Metab. 2005 May;90(5):3077-83
pubmed: 15705919
J Am Acad Dermatol. 2012 Sep;67(3):459-77
pubmed: 22018758
Trans R Soc Trop Med Hyg. 2007 Feb;101(2):183-7
pubmed: 17023012
J Clin Endocrinol Metab. 2018 Feb 1;103(2):640-648
pubmed: 29161409
J Clin Endocrinol Metab. 1991 Jan;72(1):39-45
pubmed: 1986026
Acta Obstet Gynecol Scand. 1989;68(2):185-7
pubmed: 2589043
Am J Obstet Gynecol. 1981 Feb 15;139(4):492-8
pubmed: 6258437
Proc Natl Acad Sci U S A. 1988 Jul;85(14):5244-8
pubmed: 2839838
J Steroid Biochem Mol Biol. 1995 Dec;55(5-6):465-71
pubmed: 8547171
J Clin Endocrinol Metab. 2016 Feb;101(2):364-89
pubmed: 26760044
Eur J Endocrinol. 2015 Aug;173(2):R85-91
pubmed: 25872515
N Engl J Med. 2016 Apr 7;374(14):1311-20
pubmed: 26842679
Horm Res. 2007;67(2):53-60
pubmed: 17047340