BRCA1 BRCA2 EGFR TP53 Triple negative breast cancer

Journal

International journal of molecular epidemiology and genetics
ISSN: 1948-1756
Titre abrégé: Int J Mol Epidemiol Genet
Pays: United States
ID NLM: 101525762

Informations de publication

Date de publication:
2020
Historique:
received: 24 04 2020
accepted: 05 06 2020
entrez: 28 7 2020
pubmed: 28 7 2020
medline: 28 7 2020
Statut: epublish

Résumé

Triple negative breast cancer account for 10% to 20% of all newly diagnosed breast cancer cases, this subtype is well known for its lack of estrogen, progesterone and HER2 expression unlike the other subtypes of breast cancer that usually express at least one of the three. The absence of a specific biomarker for TNBC has made his treatment very challenging and his death rates very high compared to the other subtypes. Therefore, in morocco, many studies have been conducted in the hope of finding a specific biomarker for TNBC, but none of these studies has analyzed the EGFR protein expression and its gene molecular profile and correlated the EGFR analyses results with the genetic profile of other genes. In this study, we analyzed EGFR protein expression and the molecular profile of

Identifiants

pubmed: 32714499
pmc: PMC7373717

Types de publication

Journal Article

Langues

eng

Pagination

16-25

Informations de copyright

IJMEG Copyright © 2020.

Déclaration de conflit d'intérêts

None.

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Auteurs

Farah Jouali (F)

Anoual Laboratory of Radio-Immuno Analysis Casablanca 20360, Morocco.

Fatima Zahra El Ansari (FZ)

Anoual Laboratory of Radio-Immuno Analysis Casablanca 20360, Morocco.
Biomedical Genomics and Oncogenetics Research Laboratory, Faculty of Sciences and Techniques of Tangier, University Abdelmalek Essaâdi Tangier 90000, Morocco.

Nabila Marchoudi (N)

Anoual Laboratory of Radio-Immuno Analysis Casablanca 20360, Morocco.

Amina Barakat (A)

Biomedical Genomics and Oncogenetics Research Laboratory, Faculty of Sciences and Techniques of Tangier, University Abdelmalek Essaâdi Tangier 90000, Morocco.

Hassaniya Zmaimita (H)

Clinique Le Littoral Casablanca, Maroc.

Hamza Samlali (H)

Clinique Le Littoral Casablanca, Maroc.

Jamal Fekkak (J)

Anoual Laboratory of Radio-Immuno Analysis Casablanca 20360, Morocco.

Classifications MeSH