Indeterminate dendritic cell tumor in the pancreas.
Birbeck granules
Langerin
dendritic cell tumor
histiocytic pancreatic tumor
indeterminate dendritic cell tumor
pancreatic cancer
Journal
Journal of surgical case reports
ISSN: 2042-8812
Titre abrégé: J Surg Case Rep
Pays: England
ID NLM: 101560169
Informations de publication
Date de publication:
Jul 2020
Jul 2020
Historique:
received:
19
05
2020
accepted:
09
06
2020
entrez:
28
7
2020
pubmed:
28
7
2020
medline:
28
7
2020
Statut:
epublish
Résumé
Indeterminate dendritic cell tumor (IDCT) is an extremely rare hematologic neoplastic disorder with proliferation of indeterminate dendritic cells. In the vast majority of cases, IDCTs are restricted to the skin or lymph nodes. To our knowledge, we report the first case of IDCT in the pancreas. Due to the rarity of extracutaneous IDCT, guidelines or treatment recommendations addressing their management are missing. We performed a review of literature to compare our experience to the management of other extracutaneous IDCT. Histopathological examination confirms the diagnosis of IDCT in electron microscopy and/or immunohistochemistry. Specific features are the lack of Birbeck granules and the nonreaction to Langerin antibodies. Concerning the aftercare of extracutaneous IDCT, we recommend a dermatological examination to rule out an additional cutaneous manifestation as well as annual blood examinations due to the association between IDCT and hematologic malignancies.
Identifiants
pubmed: 32714504
doi: 10.1093/jscr/rjaa208
pii: rjaa208
pmc: PMC7371254
doi:
Types de publication
Case Reports
Langues
eng
Pagination
rjaa208Informations de copyright
Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020.
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