The metabolic profile of Asinara (albino) and Sardo donkeys (pigmented) (
Albinism
Mediterranean maquis
Sun radiation
Vitamin E
Journal
PeerJ
ISSN: 2167-8359
Titre abrégé: PeerJ
Pays: United States
ID NLM: 101603425
Informations de publication
Date de publication:
2020
2020
Historique:
received:
04
03
2020
accepted:
14
05
2020
entrez:
28
7
2020
pubmed:
28
7
2020
medline:
28
7
2020
Statut:
epublish
Résumé
This study pointed to explore if variations in circulating levels of metabolites in the blood stream of no. 25 feral donkeys occur in view of the different coat color between specimens of Asinara (albino, no. 8) vs. Sardo (dun-grey, no. 17) breed. All individuals involved in this investigation are living in the nature, at Mediterranean latitudes and roam in the same areas all over the National Park of Capo Caccia, where they feed on spontaneous vegetation sources. The study was conducted during the positive photoperiod of the boreal hemisphere (peak in the month of June, 2019) to maximize the effect of exposure to the natural sun radiation and thus elicit the coping ability of albino (Asinara) in comparison with pigmented donkeys (Sardo). The biochemical profile of all donkeys was used in a Discriminant Analysis (DA) to explore if circulating levels of metabolites could point to metabolic markers for breed assignment of individuals following a canonical discriminant analysis (CANDISC). The biochemical investigation included also the determination of the circulating Vitamin E (alpha tocopherol, α-TOH), as an essential biologically active compound involved in antioxidant mechanisms, and its respective status (circulating α-TOH to total triglycerides and total cholesterol ratio). In the CANDISC, the distance between the two breeds was not significant. However, it pointed to different metabolites (UREA, total protein, total triglycerides, Zn) capable of describing biochemical patterns on each respective breed (Asinara vs. Sardo). The multivariate analysis DA carried out using 22 metabolites correctly assigned individuals to the two breeds in the 100% of cases. In view of such metabolic background, circulating α-TOH found in the bloodstream of Asinara vs. Sardo donkeys under free grazing conditions turned out to reach similar values (2.114 vs. 1.872 µg/ml, respectively,
Identifiants
pubmed: 32714654
doi: 10.7717/peerj.9297
pii: 9297
pmc: PMC7353909
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e9297Informations de copyright
© 2020 Cappai et al.
Déclaration de conflit d'intérêts
The authors declare that they have no competing interests.
Références
Vet Clin North Am Equine Pract. 2019 Dec;35(3):545-560
pubmed: 31672202
Pigment Cell Res. 2000 Oct;13(5):320-5
pubmed: 11041207
Clin Chem. 1986 May;32(5):874-6
pubmed: 3084131
Vet Rec. 1993 Feb 13;132(7):172
pubmed: 8456553
Am J Vet Res. 1990 Mar;51(3):408-13
pubmed: 2316919
Exp Cell Res. 1998 Oct 10;244(1):319-26
pubmed: 9770375
J Vet Med Sci. 1994 Feb;56(1):195-7
pubmed: 8204755
Annu Rev Plant Biol. 2006;57:711-38
pubmed: 16669779
PeerJ. 2017 Mar 28;5:e3001
pubmed: 28367363
Anim Genet. 2016 Feb;47(1):120-4
pubmed: 26763160
J Vet Intern Med. 2016 Jul;30(4):1344-50
pubmed: 27298214
Orphanet J Rare Dis. 2007 Nov 02;2:43
pubmed: 17980020
Vitam Horm. 2007;76:1-21
pubmed: 17628169
Ecol Evol. 2016 Dec 20;7(1):390-398
pubmed: 28070301
Theriogenology. 2018 Jul 15;115:84-89
pubmed: 29734125
Mol Med Today. 1996 Aug;2(8):330-5
pubmed: 8796918
J Vet Intern Med. 2012 Nov-Dec;26(6):1251-66
pubmed: 22925200
Ann Biol Clin (Paris). 1994;52(7-8):547-53
pubmed: 7840431
BMC Genomics. 2013 May 31;14:363
pubmed: 23721540
Drug Dev Ind Pharm. 2014 Mar;40(3):338-44
pubmed: 23373428
Mycotoxin Res. 2016 Nov;32(4):207-219
pubmed: 27495979
Comb Chem High Throughput Screen. 2013 Feb;16(2):142-9
pubmed: 23176060
Cornell Vet. 1990 Oct;80(4):357-79
pubmed: 2209016
Vet J. 1997 Sep;154(2):163-8
pubmed: 9308403
PLoS One. 2018 Jun 6;13(6):e0198774
pubmed: 29874272
Plant Physiol. 2003 Aug;132(4):2184-95
pubmed: 12913173
Int J Vitam Nutr Res. 1986;56(4):319-27
pubmed: 3804606
Adv Hum Genet. 1971;2:61-142
pubmed: 5005925
J Sci Food Agric. 2018 May;98(7):2801-2808
pubmed: 29131337
Tierarztl Prax. 1997 May;25(3):241-3
pubmed: 9289883
J Eur Acad Dermatol Venereol. 2003 May;17(3):251-6
pubmed: 12702061