C-Kit


Journal

Experimental physiology
ISSN: 1469-445X
Titre abrégé: Exp Physiol
Pays: England
ID NLM: 9002940

Informations de publication

Date de publication:
09 2020
Historique:
received: 20 03 2020
accepted: 24 07 2020
pubmed: 28 7 2020
medline: 21 10 2021
entrez: 28 7 2020
Statut: ppublish

Résumé

What is the central question of this study? The aim of the experiment was to highlight the regenerative capacity of bone marrow Kit Allergic asthma is a T helper (Th) 2 immunological disorder with consequential uncontrolled inflammatory responses. There is an increasing demand to use new methods for the treatment of asthma based on modulation of the Th2-to-Th1 ratio in favour of the Th1 population. Accordingly, we decided to evaluate the effects of intratracheal administration of Kit

Identifiants

pubmed: 32715538
doi: 10.1113/EP088633
doi:

Substances chimiques

GATA3 Transcription Factor 0
Gata3 protein, rat 0
T-Box Domain Proteins 0
T-box transcription factor TBX21 0
Proto-Oncogene Proteins c-kit EC 2.7.10.1

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1623-1633

Informations de copyright

© 2020 The Authors. Experimental Physiology © 2020 The Physiological Society.

Références

Aguiar, F. S., Melo, A. S., Araújo, A. M. S., Cardoso, A. P., de Souza, S. A. L., Lopes-Pacheco, M.,  … Lapa e Silva, J. R. (2020). Autologous bone marrow-derived mononuclear cell therapy in three patients with severe asthma. Stem Cell Research & Therapy, 11, 167.
Ahmadi, M., Rahbarghazi, R., Aslani, M. R., Shahbazfar, A.-A., Kazemi, M., & Keyhanmanesh, R. (2017). Bone marrow mesenchymal stem cells and their conditioned media could potentially ameliorate ovalbumin-induced asthmatic changes. Biomedicine & Pharmacotherapy, 85, 28-40.
Ahmadi, M., Rahbarghazi, R., & Shahbazfar, A.-A. (2018b). Monitoring IL-13 expression in relation to miRNA-155 and miRNA-133 changes following intra-tracheal administration of mesenchymal stem cells and conditioned media in ovalbuminsensitized rats. The Thai Journal of Veterinary Medicine, 48(3),347-355.
Ahmadi, M., Rahbarghazi, R., Shahbazfar, A.-A., Baghban, H., & Keyhanmanesh, R. (2018a). Bone marrow mesenchymal stem cells modified pathological changes and immunological responses in ovalbumin-induced asthmatic rats possibly by the modulation of miRNA155 and miRNA133. General Physiology and Biophysics, 37(3), 263-274.
Ahmadi, M., Rahbarghazi, R., Soltani, S., Aslani, M. R., & Keyhanmanesh, R. (2016). Contributory anti-inflammatory effects of mesenchymal stem cells, not conditioned media, on ovalbumin-induced asthmatic changes in male rats. Inflammation, 39, 1960-1971.
Aslani, M. R., Ghobadi, H., Panahpour, H., Ahmadi, M., Khaksar, M., & Heidarzadeh, M. (2020). Modification of lung endoplasmic reticulum genes expression and NF-kB protein levels in obese ovalbumin-sensitized male and female rats. Life Sciences, 247, 117446.
Bosnjak, B., Stelzmueller, B., Erb, K. J., & Epstein, M. M. (2011). Treatment of allergic asthma: Modulation of Th2 cells and their responses. Respiratory Research, 12, 114.
Choi, M. S., Park, S., Choi, T., Lee, G., Haam, K.-K., Hong, M.-C., … Bae, H. (2013). Bee venom ameliorates ovalbumin induced allergic asthma via modulating CD4+ CD25+ regulatory T cells in mice. Cytokine, 61, 256-265.
Dong, F., Wang, C., Duan, J., Zhang, W., Xiang, D., & Li, M. (2014). Puerarin attenuates ovalbumin-induced lung inflammation and hemostatic unbalance in rat asthma model. Evidence-Based Complementary and Alternative Medicine, 2014, 726740.
Fazel, S., Cimini, M., Chen, L., Li, S., Angoulvant, D., Fedak, P., … Li, R.-K. (2006). Cardioprotective c-kit+ cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines. The Journal of Clinical Investigation, 116, 1865-1877.
Fransioli, J., Bailey, B., Gude, N. A., Cottage, C. T., Muraski, J. A., Emmanuel, G., … Sussman, M. A. (2008). Evolution of the c-kit-positive cell response to pathological challenge in the myocardium. Stem Cells, 26, 1315-1324.
Hosseinirad, H., Rashidi, M., Moghaddam, M. M., Tebyanian, H., Nouraei, S., Mirhosseini, S. A., … Habibian, S. (2018). Stem cell therapy for lung diseases: From fundamental aspects to clinical applications. Cellular and Molecular Biology (Noisy-le-Grand, France), 64, 92-101.
Kaveh, M., Eftekhar, N., & Boskabady, M. H. (2019). The effect of alpha linolenic acid on tracheal responsiveness, lung inflammation, and immune markers in sensitized rats. Iranian journal of basic medical sciences, 22, 255-261.
Keyhanmanesh, R., Rahbarghazi, R., & Ahmadi, M. (2018a). Systemic transplantation of mesenchymal stem cells modulates endothelial cell adhesion molecules induced by ovalbumin in rat model of asthma. Inflammation, 41, 2236-45.
Keyhanmanesh, R., Rahbarghazi, R., Aslani, M. R., Hassanpour, M., & Ahmadi, M. (2018b). Systemic delivery of mesenchymal stem cells condition media in repeated doses acts as magic bullets in restoring IFN-γ/IL-4 balance in asthmatic rats. Life Sciences, 212, 30-36.
Khaksar, M., Sayyari, M., Rezaie, J., Pouyafar, A., Montazersaheb, S., & Rahbarghazi, R. (2018). High glucose condition limited the angiogenic/cardiogenic capacity of murine cardiac progenitor cells in in vitro and in vivo milieu. Cell Biochemistry and Function, 36, 346-356.
Lee, J. K., Choi, I. S., Oh, T. I., & Lee, E. (2018). Cell-surface engineering for advanced cell therapy. Chemistry (Weinheim an der Bergstrasse, Germany), 24, 15725-15743.
Loffredo, F. S., Steinhauser, M. L., Gannon, J., & Lee, R. T. (2011). Bone marrow-derived cell therapy stimulates endogenous cardiomyocyte progenitors and promotes cardiac repair. Cell Stem Cell, 8, 389-398.
Rahbarghazi, R., Keyhanmanesh, R., Aslani, M. R., Hassanpour, M., & Ahmadi, M. (2019). Bone marrow mesenchymal stem cells and condition media diminish inflammatory adhesion molecules of pulmonary endothelial cells in an ovalbumin-induced asthmatic rat model. Microvascular Research, 121, 63-70.
Rahnavard, M., Hassanpour, M., Ahmadi, M., Heidarzadeh, M., Amini, H., Javanmard, M. Z., … Safaie, N. (2019). Curcumin ameliorated myocardial infarction by inhibition of cardiotoxicity in the rat model. Journal of Cellular Biochemistry, 120, 11965-11972.
Rajabzadeh, N., Fathi, E., & Farahzadi, R. (2019). Stem cell-based regenerative medicine. Stem Cell Investigation, 6, 18-28.
Ramachandran, S., Suguihara, C., Drummond, S., Chatzistergos, K., Klim, J., Torres, E., … Young, K. C. (2015). Bone marrow-derived c-kit+ cells attenuate neonatal hyperoxia-induced lung injury. Cell Transplant, 24, 85-95.
Sánchez, A., Schimmang, T., & García-Sancho, J. (2012). Cell and Tissue Therapy in Regenerative Medicine. In: López-Larrea, C., López-Vázquez, A., & Suárez-Álvarez, B. (eds) Stem Cell Transplantation. Advances in Experimental Medicine and Biology, vol 741. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-2098-9_7
Spaziano, G., Cappetta, D., Urbanek, K., Piegari, E., Esposito, G., Matteis, M., … D'Agostino, B. (2016). New role of adult lung c-kit+ cells in a mouse model of airway hyperresponsiveness. Mediators of Inflammation, 2016, 3917471.
Urbanek, K., De Angelis, A., Spaziano, G., Piegari, E., Matteis, M., Cappetta, D., … D'Agostino, B. (2016). Intratracheal administration of mesenchymal stem cells modulates tachykinin system, suppresses airway remodeling and reduces airway hyperresponsiveness in an animal model. PLoS One, 11, e0158746.
Vajravelu, B. N., Hong, K. U., Al-Maqtari, T., Cao, P., Keith, M. C., Wysoczynski, M., … Bolli, R. (2015). C-Kit promotes growth and migration of human cardiac progenitor cells via the PI3K-AKT and MEK-ERK pathways. PLoS One, 10, e0140798.
Yang, J., & Jia, Z. (2014). Cell-based therapy in lung regenerative medicine. Regenerative Medicine Research, 2, 7.

Auteurs

Hossein Heiran (H)

Department of Physiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

Mahdi Ahmadi (M)

Tuberculosis and Lung Dsiseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Reza Rahbarghazi (R)

Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Department of Applied Cell Sciences, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.

Fatemeh Mir-Ershadi (F)

Department of Physiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Department of Physiology, Ardabil Branch, Islamic Azad University, Ardabil, Iran.

Aref Delkhosh (A)

Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Department of Pathobiology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.

Majid Khaksar (M)

Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Morteza Heidarzadeh (M)

Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Rana Keyhanmanesh (R)

Department of Physiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Neurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Articles similaires

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male
Humans Meals Time Factors Female Adult

Classifications MeSH