Re-irradiation in the thorax - An analysis of efficacy and safety based on accumulated EQD2 doses.
Esophageal cancer
Lung neoplasms
Organs at risk
Radiation dose
Re-irradiation
Journal
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
ISSN: 1879-0887
Titre abrégé: Radiother Oncol
Pays: Ireland
ID NLM: 8407192
Informations de publication
Date de publication:
11 2020
11 2020
Historique:
received:
26
03
2020
revised:
13
07
2020
accepted:
20
07
2020
pubmed:
28
7
2020
medline:
15
4
2021
entrez:
28
7
2020
Statut:
ppublish
Résumé
Thoracic re-irradiation remains a challenge regarding the balance of local efficacy and acceptable toxicities. In this retrospective analysis we analyzed dosimetrical and clinical data of patients treated with thoracic re-irradiation based on accumulated EQD2Gy doses. We retrospectively analyzed the data of 42 consecutive single-institutional patients treated with repeated courses of thoracic radiotherapy from 12/2011 to 01/2017. Accumulated EQD2 dose distributions were calculated and dose parameters for organs at risk and target volumes were analysed. The median prescription dose was 42.2 Gy (10-70.6 Gy) for all RT courses. The median Dmean of both lungs was 10.1 Gy Even though several organs at risk received maximum accumulated doses of >100 Gy
Identifiants
pubmed: 32717358
pii: S0167-8140(20)30678-2
doi: 10.1016/j.radonc.2020.07.033
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
56-62Informations de copyright
Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.