Crosslinking Dynamics and Gelation Characteristics of Photo- and Thermally Polymerized Poly(Ethylene Glycol) Hydrogels.
PEG hydrogel
UV and thermal crosslinking
gelation properties
real-time FT-IR
rheological properties
Journal
Materials (Basel, Switzerland)
ISSN: 1996-1944
Titre abrégé: Materials (Basel)
Pays: Switzerland
ID NLM: 101555929
Informations de publication
Date de publication:
23 Jul 2020
23 Jul 2020
Historique:
received:
16
06
2020
revised:
16
07
2020
accepted:
20
07
2020
entrez:
29
7
2020
pubmed:
29
7
2020
medline:
29
7
2020
Statut:
epublish
Résumé
The crosslinking behaviors and gelation features of poly(ethylene glycol) (PEG) hydrogels were scrutinized during the UV and thermal polymerizations of mixtures of poly(ethylene glycol) methacrylate (PEGMA, monomer) and poly(ethylene glycol) dimethacrylates (PEGDMAs, crosslinkers). The real-time crosslinking behavior of the PEG hydrogels was quantified as a function of the UV irradiation time and reaction temperature during the UV and thermal polymerization, respectively, using real-time FT-IR spectrometry and rotational rheometry. The gelation characteristics of UV- and thermally crosslinked hydrogels were compared through the analysis of the gel fraction, swelling ratio, surface hardness, and the loading and release of rhodamine-B. The gelation properties of the cured hydrogel films were suitably correlated with the real-time rheological properties and crosslinked network state of the PEG mixtures. The crosslinking and gelation properties of the cured hydrogels could be optimally tuned by not only the molecular weight of the crosslinker but also the UV or thermal polymerization conditions.
Identifiants
pubmed: 32717929
pii: ma13153277
doi: 10.3390/ma13153277
pmc: PMC7435459
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : The Ministry of Trade, Industry & Energy (MOTIE, Korea)
ID : No. 10067082
Organisme : The Ministry of Trade, Industry & Energy (MOTIE, Korea)
ID : No. 20004044
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