Redox responsive paclitaxel dimer for programmed drug release and selectively killing cancer cells.

Cell Line, Tumor Drug Delivery Systems Drug Liberation Humans Nanoparticles Neoplasms / drug therapy Oxidation-Reduction Paclitaxel / pharmacology Polymers / therapeutic use
Chemotherapy Redox stimulus responsive Tellurium bridged paclitaxel

Journal

Journal of colloid and interface science
ISSN: 1095-7103
Titre abrégé: J Colloid Interface Sci
Pays: United States
ID NLM: 0043125

Informations de publication

Date de publication:
15 Nov 2020
Historique:
received: 23 04 2020
revised: 16 07 2020
accepted: 17 07 2020
pubmed: 30 7 2020
medline: 22 6 2021
entrez: 30 7 2020
Statut: ppublish

Résumé

Redox stimulus responsive drug delivery systems have been widely investigated and proved to be promising prospects for efficient cancer therapy due to the abnormal high level of reactive oxygen species and glutathione in tumor microenvironment. Herein, three paclitaxel dimers (named as PTX

Identifiants

DOI: 10.1016/j.jcis.2020.07.086 PMID: 32721635
pubmed: 32721635
pii: S0021-9797(20)30966-8
doi: 10.1016/j.jcis.2020.07.086
pii:
doi:

Substances chimiques

Polymers 0
Paclitaxel P88XT4IS4D

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

785-793

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Rui Xia (R)

State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, Jilin 130022, PR China; University of Science and Technology of China, Hefei 230026, PR China.

Qing Pei (Q)

State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, Jilin 130022, PR China; University of Science and Technology of China, Hefei 230026, PR China.

Jian Wang (J)

State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, Jilin 130022, PR China; University of Science and Technology of China, Hefei 230026, PR China.

Zhanfeng Wang (Z)

Department of Neurosurgery, China-Japan Union Hospital of Jilin University, Changchun, Jilin 130033, PR China.

Xiuli Hu (X)

State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, Jilin 130022, PR China. Electronic address: lily@ciac.ac.cn.

Zhigang Xie (Z)

State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, Jilin 130022, PR China; University of Science and Technology of China, Hefei 230026, PR China. Electronic address: xiez@ciac.ac.cn.

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Classifications MeSH

questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › Redox responsive paclitaxel dimer for...
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Systèmes de délivrance de médicaments › Redox responsive paclitaxel dimer for...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Pharmacocinétique › Libération de médicament › Redox responsive paclitaxel dimer for...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Redox responsive paclitaxel dimer for...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Nanostructures › Nanoparticules › Redox responsive paclitaxel dimer for...
questionsmedicales.fr › Tumeurs › Redox responsive paclitaxel dimer for...
questionsmedicales.fr › Métabolisme › Métabolisme énergétique › Oxydoréduction › Redox responsive paclitaxel dimer for...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Terpènes › Diterpènes › Taxoïdes › Paclitaxel › Redox responsive paclitaxel dimer for...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Polymères › Redox responsive paclitaxel dimer for...