Generations of genomes: advances in paleogenomics technology and engagement for Indigenous people of the Americas.
Journal
Current opinion in genetics & development
ISSN: 1879-0380
Titre abrégé: Curr Opin Genet Dev
Pays: England
ID NLM: 9111375
Informations de publication
Date de publication:
06 2020
06 2020
Historique:
received:
02
03
2020
revised:
18
06
2020
accepted:
22
06
2020
pubmed:
30
7
2020
medline:
3
7
2021
entrez:
30
7
2020
Statut:
ppublish
Résumé
For decades, scientists have collected genomic information from Indigenous peoples and their ancestors with the goal of elucidating human migration events, understanding ancestral origins, and identifying ancestral variants contributing to disease. However, such studies may not have offered much benefit to the Indigenous groups who contributed DNA, and many have instead perpetuated stereotypes and other harms. With recent advances in genomic technology facilitating the study of both ancient and present-day DNA, researchers and Indigenous communities have new opportunities to begin collaboratively addressing important questions about human health and history. Yet, while there are increased efforts to ethically engage Indigenous communities, more work is still needed as the discipline struggles to absolve itself of the racialized science and extractive biocolonialism that defined its past.
Identifiants
pubmed: 32721847
pii: S0959-437X(20)30110-6
doi: 10.1016/j.gde.2020.06.010
pmc: PMC7484015
mid: NIHMS1608230
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
91-96Subventions
Organisme : NHGRI NIH HHS
ID : K01 HG008818
Pays : United States
Organisme : NIGMS NIH HHS
ID : P20 GM103442
Pays : United States
Informations de copyright
Copyright © 2020 Elsevier Ltd. All rights reserved.
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