Polymer Nanomedicines with Ph-Sensitive Release of Dexamethasone for the Localized Treatment of Inflammation.
HPMA
adjuvant-induced arthritis
dexamethasone
drug delivery
inflammation
passive targeting
polymer conjugate
Journal
Pharmaceutics
ISSN: 1999-4923
Titre abrégé: Pharmaceutics
Pays: Switzerland
ID NLM: 101534003
Informations de publication
Date de publication:
25 Jul 2020
25 Jul 2020
Historique:
received:
15
06
2020
revised:
14
07
2020
accepted:
16
07
2020
entrez:
30
7
2020
pubmed:
30
7
2020
medline:
30
7
2020
Statut:
epublish
Résumé
Polymer-drug conjugates have several advantages in controlled drug delivery to inflammation as they can accumulate and release the drug in inflamed tissues or cells, which could circumvent the shortcomings of current therapy. To improve the therapeutic potential of polymer-drug conjugates in joint inflammation, we synthesized polymer conjugates based on
Identifiants
pubmed: 32722403
pii: pharmaceutics12080700
doi: 10.3390/pharmaceutics12080700
pmc: PMC7465548
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Grantová Agentura České Republiky
ID : 19-00956Y
Organisme : Ministerstvo Školství, Mládeže a Tělovýchovy
ID : MSMT LTAUSA18083
Organisme : Ministerstvo Školství, Mládeže a Tělovýchovy
ID : BIOCEV-FAR LQ1604
Organisme : Ministerstvo Školství, Mládeže a Tělovýchovy
ID : CZ.1.05/1.1.00/02.0109
Organisme : France Life Imaging
ID : ANR-11-INBS-0006
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