[Brain abscess and Osler-Weber-Rendu syndrome: Do not forget to look for pulmonary arteriovenous malformations].
Abcès cérébral et maladie de Rendu-Osler-Weber : pensez à rechercher des malformations artério-veineuses pulmonaires.
Aged
Anti-Bacterial Agents
/ therapeutic use
Arteriovenous Fistula
/ diagnosis
Arteriovenous Malformations
/ diagnosis
Brain Abscess
/ diagnosis
Embolization, Therapeutic
Female
Humans
Pulmonary Artery
/ abnormalities
Pulmonary Veins
/ abnormalities
Telangiectasia, Hereditary Hemorrhagic
/ complications
Abcès cérébral
Arteriovenous malformations
Brain abscess
Embolisation
Embolization
Hereditary hemorrhagic telangiectasia
Maladie de Rendu-Osler
Malformation artério-veineuse
Osler-Rendu-Weber syndrome
Télangiectasie hémorragique héréditaire
Journal
La Revue de medecine interne
ISSN: 1768-3122
Titre abrégé: Rev Med Interne
Pays: France
ID NLM: 8101383
Informations de publication
Date de publication:
Nov 2020
Nov 2020
Historique:
received:
25
02
2020
revised:
02
06
2020
accepted:
20
06
2020
pubmed:
30
7
2020
medline:
23
2
2021
entrez:
30
7
2020
Statut:
ppublish
Résumé
Osler-Rendu-Weber syndrome or hereditary hemorrhagic telangiectasia affects between 1/5000 and 1/8000 people. It is characterized by presence of recurrent epistaxis, mucocutaneous telangiectasia and visceral arteriovenous malformations. It is a genetic disease with autosomal dominant transmission inducing an endothelial cells hyper-proliferation. A 68-year-old women with Osler-Rendu-Weber syndrome was referred for management of general impairment with confusional syndrome and hyperthermia. Various examinations have allowed us to conclude at diagnosis of brain abscess with ventriculitis probably favored by right-left shunt secondary to pulmonary arteriovenous malformations. Evolution was favorable after antibiotic treatment and endovascular embolization. In case of brain abscess without obvious promoting factor, don't forget to looking for a right-left shunt providing septic or aseptic emboli. Furthermore, diagnosis of Rendu-Osler-Weber syndrome should be considered presence of telangiectasias and/or epistaxis.
Identifiants
pubmed: 32723482
pii: S0248-8663(20)30220-4
doi: 10.1016/j.revmed.2020.06.009
pii:
doi:
Substances chimiques
Anti-Bacterial Agents
0
Types de publication
Case Reports
Journal Article
Langues
fre
Sous-ensembles de citation
IM
Pagination
776-779Informations de copyright
Copyright © 2020. Published by Elsevier Masson SAS.