Shape memory polyurethane-urea foams with improved toughness.
polyurethane
shape memory polymer foam
Journal
Journal of applied polymer science
ISSN: 0021-8995
Titre abrégé: J Appl Polym Sci
Pays: United States
ID NLM: 9891577
Informations de publication
Date de publication:
10 Apr 2019
10 Apr 2019
Historique:
entrez:
30
7
2020
pubmed:
10
4
2019
medline:
10
4
2019
Statut:
ppublish
Résumé
Current vascular aneurysm treatments often require either highly invasive strategy to surgically occlude an aneurysm or endovascular occlusion via metal coils. While endovascular coils are safer, they have limited efficacy. Endovascular coils that are integrated with shape memory polymer (SMP) foams have the potential to improve occlusion and reduce coil risks; however, the mechanical performance and limited homogeneity of SMP foams can hinder their effective use. To address this issue, SMP foams are synthesized using the monomer diethanolamine (DEA) in place of triethanolamine (TEA) to provide improved mechanical properties for medical device applications. Mechanical testing and micro-fracture analysis were performed on DEA and TEA foams. DEA foams show improved toughness and reduced micro-fractures compared to the control. This work presents the utility of DEA in SMP synthesis to enable the potential production of safer aneurysm treatment.
Identifiants
pubmed: 32724263
doi: 10.1002/app.47268
pmc: PMC7386400
mid: NIHMS1607973
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : NINDS NIH HHS
ID : U01 NS089692
Pays : United States
Déclaration de conflit d'intérêts
CONFLICT OF INTEREST Andrew C. Weems holds stock in Shape Memory Medical, Inc. (SMM), which holds a license for the shape memory polymers in this work. Sayyeda M. Hasan is currently employed by SMM and also holds stock options. Duncan Maitland owns stock and is on the board of directors at SMM.
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