Effectiveness of Factor XIII Infusion in Treatment of Refractory Ureteral Leakage after Kidney Transplantation.
Journal
Case reports in transplantation
ISSN: 2090-6943
Titre abrégé: Case Rep Transplant
Pays: United States
ID NLM: 101591863
Informations de publication
Date de publication:
2020
2020
Historique:
received:
20
03
2020
revised:
19
06
2020
accepted:
03
07
2020
entrez:
30
7
2020
pubmed:
30
7
2020
medline:
30
7
2020
Statut:
epublish
Résumé
Despite the evolution of transplantation techniques, urological complications are common and result in loss of graft. We report the case of a 57-year-old man who developed continuous urine leakage despite pyeloureteral neoanastomosis and stenting after kidney transplantation from his dizygotic twin. Suspecting ureteral leakage, we performed pyeloureteral neoanastomosis using his native right ureter and a ureteral stent 5 days after the kidney transplant. However, urine leakage continued for several days. Because the plasma factor XIII level decreased to 48%, we administered factor XIII products (Fibrogammin P; CSL Behring, King of Prussia, PA) after the surgery. Although its utility and safety in patients with renal failure and/or transplantation are unclear, urine leakage stopped after the infusion of fibrogammin without any side effects. This is the first case report of the use of factor XIII for refractory urine leakage after kidney transplantation. Although further studies are needed, administration of factor XIII products could be one option for refractory urine leakage after transplantation.
Identifiants
pubmed: 32724697
doi: 10.1155/2020/1780760
pmc: PMC7381963
doi:
Types de publication
Case Reports
Langues
eng
Pagination
1780760Informations de copyright
Copyright © 2020 Ryoichi Maenosono et al.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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