First Clinical Study with AP30663 - a K
Adolescent
Adult
Anti-Arrhythmia Agents
/ administration & dosage
Atrial Fibrillation
/ drug therapy
Dose-Response Relationship, Drug
Double-Blind Method
Electrocardiography
/ drug effects
Half-Life
Healthy Volunteers
Heart Rate
/ drug effects
Humans
Infusions, Intravenous
Injection Site Reaction
/ diagnosis
Male
Middle Aged
Potassium Channels, Calcium-Activated
/ antagonists & inhibitors
Severity of Illness Index
Young Adult
Journal
Clinical and translational science
ISSN: 1752-8062
Titre abrégé: Clin Transl Sci
Pays: United States
ID NLM: 101474067
Informations de publication
Date de publication:
11 2020
11 2020
Historique:
received:
26
02
2020
accepted:
22
05
2020
pubmed:
30
7
2020
medline:
16
10
2021
entrez:
30
7
2020
Statut:
ppublish
Résumé
Pharmacological cardioversion of atrial fibrillation (AF) is frequently inefficacious. AP30663, a small conductance Ca
Identifiants
pubmed: 32725783
doi: 10.1111/cts.12835
pmc: PMC7719388
doi:
Substances chimiques
Anti-Arrhythmia Agents
0
Potassium Channels, Calcium-Activated
0
Types de publication
Clinical Trial, Phase I
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
1336-1344Subventions
Organisme : Wellcome Trust
ID : 200450/Z/16/Z
Pays : United Kingdom
Informations de copyright
© 2020 The Authors. Clinical and Translational Science published by Wiley Periodicals LLC on behalf of the American Society for Clinical Pharmacology and Therapeutics.
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