Effects of Vitamin B2 Supplementation in Broilers Microbiota and Metabolome.
broiler
metabolome
microbiota
short chain fatty acids
vitamin B2
Journal
Microorganisms
ISSN: 2076-2607
Titre abrégé: Microorganisms
Pays: Switzerland
ID NLM: 101625893
Informations de publication
Date de publication:
27 Jul 2020
27 Jul 2020
Historique:
received:
03
06
2020
revised:
24
07
2020
accepted:
24
07
2020
entrez:
31
7
2020
pubmed:
31
7
2020
medline:
31
7
2020
Statut:
epublish
Résumé
The study of the microbiome in broiler chickens holds great promise for the development of strategies for health maintenance and performance improvement. Nutritional strategies aimed at modulating the microbiota-host relationship can improve chickens' immunological status and metabolic fitness. Here, we present the results of a pilot trial aimed at analyzing the effects of a nutritional strategy involving vitamin B2 supplementation on the ileum, caeca and litter microbiota of Ross 308 broilers, as well as on the metabolic profile of the caecal content. Three groups of chickens were administered control diets and diets supplemented with two different dosages of vitamin B2. Ileum, caeca, and litter samples were obtained from subgroups of birds at three time points along the productive cycle. Sequencing of the 16S rRNA V3-V4 region and NMR metabolomics were used to explore microbiota composition and the concentration of metabolites of interest, including short-chain fatty acids. Vitamin B2 supplementation significantly modulated caeca microbiota, with the highest dosage being more effective in increasing the abundance of health-promoting bacterial groups, including
Identifiants
pubmed: 32727134
pii: microorganisms8081134
doi: 10.3390/microorganisms8081134
pmc: PMC7464963
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Università di Bologna
ID : 77/2018
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