The generic Informed Consent Service gICS

Consent management GDPR General data protection regulation Informed consent

Journal

Journal of translational medicine
ISSN: 1479-5876
Titre abrégé: J Transl Med
Pays: England
ID NLM: 101190741

Informations de publication

Date de publication:
29 07 2020
Historique:
received: 05 06 2020
accepted: 21 07 2020
entrez: 31 7 2020
pubmed: 31 7 2020
medline: 15 5 2021
Statut: epublish

Résumé

Defining and protecting participants' rights is the aim of several ethical codices and legal regulations. According to these regulations, the Informed Consent (IC) is an inevitable element of research with human subjects. In the era of "big data medicine", aspects of IC become even more relevant since research becomes more complex rendering compliance with legal and ethical regulations increasingly difficult. Based on literature research and practical experiences gathered by the Institute for Community Medicine (ICM), University Medicine Greifswald, requirements for digital consent management systems were identified. To address the requirements, the free-of-charge, open-source software "generic Informed Consent Service" (gICS Since the consent's content is a prerequisite for securing participants' rights, application of gICS is no guarantee for legal compliance. However, gICS supports fine-granular consents and accommodation of differentiated consent states, which can be directly exchanged between systems, allowing automated data processing. gICS simplifies and supports sustained IC management as a major key to successfully conduct studies and build trust in research with human subjects. Therefore, interested researchers are invited to use gICS and provide feedback for further improvements.

Sections du résumé

BACKGROUND
Defining and protecting participants' rights is the aim of several ethical codices and legal regulations. According to these regulations, the Informed Consent (IC) is an inevitable element of research with human subjects. In the era of "big data medicine", aspects of IC become even more relevant since research becomes more complex rendering compliance with legal and ethical regulations increasingly difficult.
METHODS
Based on literature research and practical experiences gathered by the Institute for Community Medicine (ICM), University Medicine Greifswald, requirements for digital consent management systems were identified.
RESULTS
To address the requirements, the free-of-charge, open-source software "generic Informed Consent Service" (gICS
DISCUSSION
Since the consent's content is a prerequisite for securing participants' rights, application of gICS is no guarantee for legal compliance. However, gICS supports fine-granular consents and accommodation of differentiated consent states, which can be directly exchanged between systems, allowing automated data processing.
CONCLUSION
gICS simplifies and supports sustained IC management as a major key to successfully conduct studies and build trust in research with human subjects. Therefore, interested researchers are invited to use gICS and provide feedback for further improvements.

Identifiants

pubmed: 32727514
doi: 10.1186/s12967-020-02457-y
pii: 10.1186/s12967-020-02457-y
pmc: PMC7391490
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

287

Références

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Auteurs

Henriette Rau (H)

Trusted Third Party of the University Medicine Greifswald, Ellernholzstr. 1-2, 17475, Greifswald, Germany. henriette.rau@uni-greifswald.de.

Lars Geidel (L)

Trusted Third Party of the University Medicine Greifswald, Ellernholzstr. 1-2, 17475, Greifswald, Germany.

Martin Bialke (M)

Institute for Community Medicine Section Epidemiology of Health Care and Community Health, University Medicine Greifswald, Ellernholzstr. 1-2, 17475, Greifswald, Germany.

Arne Blumentritt (A)

Trusted Third Party of the University Medicine Greifswald, Ellernholzstr. 1-2, 17475, Greifswald, Germany.

Martin Langanke (M)

Protestant University of Applied Sciences in Bochum, Immanuel-Kant-Str. 18-20, 44803, Bochum, Germany.

Wenke Liedtke (W)

Faculty of Theology, University of Greifswald, Am Rubenowplatz 2-3, 17487, Greifswald, Germany.

Sandra Pasewald (S)

Trusted Third Party of the University Medicine Greifswald, Ellernholzstr. 1-2, 17475, Greifswald, Germany.

Dana Stahl (D)

Trusted Third Party of the University Medicine Greifswald, Ellernholzstr. 1-2, 17475, Greifswald, Germany.

Thomas Bahls (T)

Institute for Community Medicine Section Epidemiology of Health Care and Community Health, University Medicine Greifswald, Ellernholzstr. 1-2, 17475, Greifswald, Germany.

Christian Maier (C)

Chair of Medical Informatics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Wetterkreuz 13, 91058, Erlangen, Germany.

Hans-Ulrich Prokosch (HU)

Chair of Medical Informatics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Wetterkreuz 13, 91058, Erlangen, Germany.

Wolfgang Hoffmann (W)

Institute for Community Medicine Section Epidemiology of Health Care and Community Health, University Medicine Greifswald, Ellernholzstr. 1-2, 17475, Greifswald, Germany.

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Classifications MeSH