HIV-1
IP6
assembly
capsid
immature
mature
polyanion
Journal
Journal of virology
ISSN: 1098-5514
Titre abrégé: J Virol
Pays: United States
ID NLM: 0113724
Informations de publication
Date de publication:
29 09 2020
29 09 2020
Historique:
received:
19
05
2020
accepted:
22
07
2020
pubmed:
31
7
2020
medline:
16
12
2020
entrez:
31
7
2020
Statut:
epublish
Résumé
Proper assembly and disassembly of both immature and mature HIV-1 hexameric lattices are critical for successful viral replication. These processes are facilitated by several host-cell factors, one of which is myo-inositol hexaphosphate (IP6). IP6 participates in the proper assembly of Gag into immature hexameric lattices and is incorporated into HIV-1 particles. Following maturation, IP6 is also likely to participate in stabilizing capsid protein-mediated mature hexameric lattices. Although a structural-functional analysis of the importance of IP6 in the HIV-1 life cycle has been reported, the effect of IP6 has not yet been quantified. Using two
Identifiants
pubmed: 32727872
pii: JVI.00991-20
doi: 10.1128/JVI.00991-20
pmc: PMC7527058
pii:
doi:
Substances chimiques
Polyelectrolytes
0
Polymers
0
gag Gene Products, Human Immunodeficiency Virus
0
polyanions
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2020 American Society for Microbiology.
Références
Retrovirology. 2014 Oct 30;11:94
pubmed: 25365920
Proteins. 2013 Aug;81(8):1377-85
pubmed: 23504872
J Biol Chem. 2013 Jan 18;288(3):1511-20
pubmed: 23184932
J Virol. 1998 Nov;72(11):9313-7
pubmed: 9765481
Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10875-9
pubmed: 11526217
Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18625-30
pubmed: 25518861
Nat Struct Mol Biol. 2004 Jul;11(7):672-5
pubmed: 15208690
J Virol. 2004 Sep;78(18):9675-88
pubmed: 15331700
Science. 2016 Dec 16;354(6318):1434-1437
pubmed: 27980210
Nature. 2013 May 30;497(7451):643-6
pubmed: 23719463
J Virol. 1994 Aug;68(8):4927-36
pubmed: 8035491
J Virol. 2003 May;77(9):5439-50
pubmed: 12692245
Viruses. 2018 Apr 20;10(4):
pubmed: 29677171
Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11364-9
pubmed: 16840558
Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19114-9
pubmed: 19861549
Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11090-5
pubmed: 19549863
Sci Rep. 2019 Nov 19;9(1):17076
pubmed: 31745222
Nature. 2000 Sep 21;407(6802):409-13
pubmed: 11014200
Elife. 2016 Jul 14;5:
pubmed: 27416583
Nature. 2011 Jan 20;469(7330):424-7
pubmed: 21248851
Science. 2016 Jul 29;353(6298):506-8
pubmed: 27417497
PLoS Pathog. 2014 Oct 30;10(10):e1004459
pubmed: 25356722
Nature. 2018 Aug;560(7719):509-512
pubmed: 30069050
PLoS Pathog. 2010 Nov 18;6(11):e1001200
pubmed: 21124996
Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):E11751-E11760
pubmed: 30478053
Virology. 2015 Dec;486:78-87
pubmed: 26410239
J Virol. 1998 Jun;72(6):4798-810
pubmed: 9573245
J Microbiol Methods. 2014 Nov;106:67-71
pubmed: 25149690
Proc Natl Acad Sci U S A. 1990 Jan;87(2):523-7
pubmed: 2405382
J Virol. 1995 Oct;69(10):6487-97
pubmed: 7666550
EMBO J. 2000 Jan 4;19(1):103-13
pubmed: 10619849
Science. 1999 Jan 1;283(5398):80-3
pubmed: 9872746
Nature. 2016 Aug 18;536(7616):349-53
pubmed: 27509857
Cell. 2007 Oct 5;131(1):70-9
pubmed: 17923088
J Virol. 2012 Feb;86(4):1988-98
pubmed: 22171253
Cell Rep. 2019 Dec 17;29(12):3983-3996.e4
pubmed: 31851928
Cell. 2009 Nov 13;139(4):780-90
pubmed: 19914170
Nature. 2015 Jan 22;517(7535):505-8
pubmed: 25363765
Proc Natl Acad Sci U S A. 2004 Oct 12;101(41):14889-94
pubmed: 15465916
J Virol. 2004 Mar;78(5):2545-52
pubmed: 14963157
Science. 2015 Jul 3;349(6243):99-103
pubmed: 26044298
EMBO J. 2007 Apr 18;26(8):2218-26
pubmed: 17396149
J Virol. 1994 Apr;68(4):2556-69
pubmed: 8139035
J Mol Biol. 2007 Jul 13;370(3):585-97
pubmed: 17532005
J Mol Biol. 2007 Jan 19;365(3):799-811
pubmed: 17098251
J Virol. 2006 Jul;80(14):7089-99
pubmed: 16809314
Elife. 2018 May 31;7:
pubmed: 29848441